化学生物学 Chemical Biology
韩守法课题组: 生物信号响应分子与材料

Shou-Fa HAN — Bioresponsive Sensor for Cancer Imaging

Group Members

Associate Professor Yang Liu (杨 柳)

Selected Publications

  1. Responsive hetero-organelle partition conferred fluorogenic sensing of mitochondrial depolarization; Zhongwei Xue, Hu Zhao, Jian Liu, Jiahuai Han, Shoufa Han*, Chem. Sci. 2017, 8, 1915-1921
  2. Imaging lysosomal pH alteration in stressed cells with a sensitive ratiometric fluorescence sensor, Zhongwei Xue, Hu Zhao, Jian Liu, aJiahuai Han, Shoufa Han*, ACS Sensors. 2017, 2, 436-442
  3. Redirecting immunity via covalently incorporated immunogenic sialic acid on the tumor cell surface, Bijuan Lin, Xuanjun Wu, Hu Zhao, Yunpeng Tian, Jian Liu, Jiahuai Han, and Shoufa Han*, Chem. Sci. 2016, 7, 3737-3741
  4. A carbohydrate-grafted nanovesicle for fluorescence and acoustic imaging of tumors, Xuanjun Wu, Bijuan Lin, Mingzhu Yu, Jiahuai Han, Shoufa Han*, Chem. Sci. 2015, 6, 2002-2009
  5. A sialic acid-targeted near-infrared theranostic for signal activation based intraoperative tumor ablation; Xuanjun Wu, Mingzhu Yu, Bijuan Lin, Hongjie Xing, Jiahuai Han, and Shoufa Han*, Chem. Sci. 2015, 6, 798-803
  6. Optical Tracking of Phagocytosis with an Activatable Profluorophore Metabolically Incorporated into Bacterial Peptidoglycan; Yunpeng Tian, Mingzu Yu, Zhu Li, Jiahuai Han, Liu Yang*, Shoufa Han*, Anal. Chem., 2015, 87, 8381-8386
  7. Lysosomal pH Decrease in Inflammatory Cells Used To Enable Activatable Imaging of Inflammation with a Sialic Acid Conjugated Profluorophore; Mingzhu Yu, Xuanjun Wu, Bijuan Lin, Jiahuai Han, Liu Yang, and Shoufa Han*, Anal. Chem., 2015, 87, 6688-6695
  8. A self-referenced nanodosimeter for reaction based ratiometric detection of hypochlorous acid in living cells,Xuanjun Wu, Zhu Li, Yuhui Yang, Liu Yang, Jiahuai Han and Shoufa Han* Chem. Sci., 2013, 460-467
  9. Rhodamine-deoxylactam functionalized poly[styrene-alter-(maleic acid)] as lysosome activatable probes for intraoperative detection of tumors,Zhu Li, Yunlong Song, Yuhui Yang, Liu Yang, Xiaohong Huang, Jiahuai Han and Shoufa Han*, Chem. Sci., 2012, 2, 2941-2948
  10. Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking;  Shoufa Han, Brian E. Collins, Per Bengtson, and James C. Paulson*, Nat. Chem. Biol., 2005, 1, 93-97

Selected Target of Current Interests


韩守法 教授、博士生导师

 
博士(University of Toledo,2003)
硕士(北京科学院化学研究所,1999)
学士(北京大学,1996)
博士后(The Scripps Research Institute)

电话:(0592)2181728 (实验室)
电子邮箱:shoufa@xmu.edu.cn

研究兴趣:基于有机小分子的疾病关联细胞器变化分析与功能调控,糖探针调控炎症反应与肿瘤免疫识别(有机、化学生物学专业招生)

 




Shou-Fa HAN Professor

 
Post-doc (2003-2006), The Scripps Research Institute, USA
Ph. D. (2003), The University of Toledo, USA;
M.S. (1999), Institute of Chemistry, Chinese Academyof Science, Beijing
B.S. Beijing University, China.

Research Interests: microbicides against sexual HIV-1 transmission; nanoparticle mediated protein delivery and bioresponsive materials foe cell signaling studies