有机化学 Organic Chemistry
詹庄平课题组: 有机合成

Zhuang-Ping ZHAN — Organic Synthesis

Group Members
Associate Professor Min Lin (林敏), Associate Professor Li Chen (陈立)

Selected Publications

  1. Synthesis of 5,6-Dihydropyrazolo[1,5?c]quinazolines through Gold-Catalyzed ChemoselectiveBicyclization of N?Propargylic Sulfonylhydrazones.Hai-Tao Tang, Kai Xiong, Ren-Hao Li, Zong-Cang Ding, and Zhuang-Ping Zhan*, Org. Lett.2015, 17, 326-329.
  2. Synthesis of Polysubstituted Pyrazoles by aPlatinum-Catalyzed Sigmatropic Rearrangement/Cyclization Cascade. Jia-Jie Wen,Hai-Tao Tang, Kai Xiong, Zong-Cang Ding, and Zhuang-Ping Zhan*, Org. Lett.2014, 16, 5940?5943.
  3. Base-Catalyzed N_N Bond Cleavage of Hydrazones:Synthesis of a-AminoKetones. Hai-Tao Tang, Yun-Bing Zhou, Yu Zhu, Hong-ChaoSun, Min Lin, and Zhuang-Ping Zhan*,Chem. Asian J. 2014, 9, 1278 -1281.
  4. Selective synthesis of 4-(sulfonyl)-methyl-1Hpyrazolesand (E)-4,5-dihydro-1H-pyrazoles from N-allenic sulfonylhydrazones. Yu Zhu, Jun-JieHong, Yun-Bin Zhou, Yu-Wei Xiao, Min Lin and Zhuang-Ping Zhan*,Org.Biomol. Chem. 2014, 12, 3797–3801.
  5. Silver(I)-catalyzed annulation for the regioselectivesynthesis of N-imino-γ-carbolinium ylides from hydrazones of indole-3-carbonylderivatives and propargylic alcohols. Yu Zhu, Xin-Rui Shen, Hai-Tao Tang, MinLin and Zhuang-Ping Zhan*, Org. Biomol. Chem. 2014, 12, 9514-9518.
  6. Lewis Base Catalyzed Synthesis of Multisubstituted4-Sulfonyl-1 H-Pyrazole Involving a Novel 1, 3-Sulfonyl Shift. Yu Zhu, Wen-TingLu, Hong-Cao Sun, Zhuang-Ping Zhan*,Org.Lett. 2013, 15,4146-4149.
  7. Copper (I)-Catalyzed Stereoselective Synthesis of(1E,3E)-2-Sulfonyl-1,3-dienes from N-Propargylic Sulfonohydrazones. Yu Zhu, Hai-Tao Tang, Zhuang-Ping Zhan*, Adv. Synth. Catal.2013,355, 1291-1296.
  8. One-Pot Synthesis of Pyrazoles through a Four-StepCascade Sequence.Lu Hao, Junjie Hong, Jun Zhu, Zhuang-Ping Zhan*,Chem.Eur. J.2013, 19, 5715-5720.
  9. Chemoselective synthesis of substituted pyrazolesthrough AgOTf-catalyzed cascade propargylicsubstitution-cyclization-aromatization. Su-Xia Xu, Lu Hao, Tao Wang,Zong-Cang Ding, Zhuang-Ping Zhan*,Org.Biomol. Chem.2013, 11, 294-298.
  10. Synthesis ofAcrylonitriles through an FeCl3-Catalyzed Domino Propargylic Substitution/Aza-Meyer–SchusterRearrangement Sequence. Lu Hao, Feng Wu, Zong-Cang Ding, Su-Xia Xu, Yan-Li Ma,Li Chen, and Zhuang-Ping Zhan*,Chem. Eur. J.2012, 18, 6453–6456.
  11. The Synthesis of Aromatic Heterocycles from Propargylic Compounds. Wen Jia-Jie, Yu Zhu, Zhuang-Ping Zhan*, Asian J. Org. Chem., 2012,1, 108-129.(综述)
  12. Microwave-assisted synthesis of2-aminopyrimidines from silica gel-adsorbed propargyl alcohols and guanidine,Feng Wu, Zhuang-Ping Zhan*,Heterocycles 2012,85, 1891-1896.
  13. Atom-Economical Chemoselective Synthesis of 1,4-Diynesand Polysubstituted Furans/Pyrroles from Propargyl Alcohols and TerminalAlkynes. Tao Wang, Xin-liang Chen, Li Chen, and Zhuang-ping Zhan*,Org. Lett.2011, 13, 3324-3327.
  14. Nucleophilic Substitution of SecondaryAlkyl-Substituted Propargyl Acetates: An Economic and Practical IndiumTrichloride Catalyzed Access. Min Lin , Lu Hao, Xiao-tao Liu, Qing-zhen Chen,Feng Wu, Ping Yan, Su-xia Xu, Xin-liang Chen, Jia-jie Wen, Zhuang-ping Zhan*, Synlett2011,665-670.
  15. Copper(II)-Catalyzed Synthesis of Pyrimidines fromPropargylic Alcohols and Amidine: A Propargylation–Cyclization–Oxidation TandemReaction. Min Lin, Qing-zhen Chen, Yu Zhu, Xin-liang Chen, Ji-jun Cai,Ying-ming Pan,Zhuang-ping Zhan*,Synlett2011, 1179-1183.
  16. The Construction ofFive-Membered Heterocycles by Transition Metal-Catalyzed Cyclization ofPropargylic Compounds.Lu Hao and Zhuang-Ping Zhan*, Current Organic Chemistry2011, 15, 1625-1643(综述)
  17. Chemoselective Cascade Synthesis of N-FusedHeterocycles via Silver(I) Triflate-Catalyzed Friedel–Crafts/N-C Bond FormationSequence. Lu Hao, Yingming Pan, Tao Wang, Min Lin, Li Chen, Zhuang-ping Zhan*,Adv. Synth. Catal.,2010, 352, 3215-3222.
  18. Solvent-Free Solid Acid-Catalyzed NucleophilicSubstitution of Propargylic Alcohols: A Green Approach for the Synthesis of 1,4-diynes. Tao Wang, Rui-da Ma and Zhuang-ping Zhan*, Green Chem. 2010, 12, 1576–1579.
  19. Facile one-pot synthesis of three differentsubstituted thiazoles from propargylic alcohols. Xun Gao, Ying-ming Pan, MinLin, Li Chen and Zhuang-ping Zhan*. Org. Biomol. Chem. 2010, 8, 3259–3266. ( highlightedby Synfacts,Synfacts, 2010, 9, 996)
  20. One-pot highly efficient synthesis of substitutedpyrroles and N-bridgehead pyrroles by zinc-catalyzed multicomponent reaction. Xiao-taoLiu, Lu Hao, Min Lin, Li Chen and Zhuang-pingZhan*. Org. Biomol. Chem. 2010, 8, 3064–3072.

詹庄平 教授、博士生导师

 
博士(浙江大学,1998)
硕士(南开大学,1991)
学士(浙江大学,1985)
博士后(台湾清华大学,美国Johns Hopkins University)

电话:(0592)2180318 (办公室)
   (0592)2187195 (实验室)
电子邮箱:zpzhan@xmu.edu.cn
课题组网站:
  http://chem-zzp.xmu.edu.cn/

研究兴趣:有机合成:基于炔丙醇为原料的杂环化合物新合成方法研究; 药物合成:应用新合成方法合成药物和天然化合物; 香料合成:天然香料的研发

 




Zhuang-Ping ZHAN Professor

 
Ph. D. (1998), Zhejiang University
M.S. (1991), Nankai University
B.S. (1985) Zhejiang University
Post-doc Tsinghua University (taiwan), Johns Hopkins University

Tel:(0592)2180318(O)
   (0592)2187195(L)
Email: zpzhan@xmu.edu.cn
Web: http://chem-zzp.xmu.edu.cn/

Research Interests:The development of new synthetic methods, Organometallic chemistry