Pei-Qiang Huang

College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian 361005, China;
Phones: 011-86-592-218-2240 (o); 86-1360-6083-881 (cell)

Education and Professional Experience:

  • B.S. in Chemistry Xiamen University 1978-1982
  • D.E.A. in Organic Chemistry Universite de Montpellier II, France 1983-1984
  • Ph.D. in Organic Chemistry University of Paris-XI, France, 1987 L*institut de Chimie des Substances Naturelles, CNRS 1984-1987
  • Postdoctoral Fellow Shanghai Institute of Organic Chemistry, CAS 1988-1990

Academic Appointments:

  • 1990-1993 Associate Professor, Xiamen University
  • 1993-present Professor, Xiamen University
  • 2003-2007 Dean, College of Chemistry and Chemical Engineering, XMU
  • 2008-present Dean, College of Chemistry and Chemical Engineering, XMU

Major Honors and Awards:

  • Fellow of RSC, 2005-present
  • Fund for Distinguished Young Investigator National Scientific Foundation, 1996
  • Hong Kong Qiu Shi Scientific & Technological Foundation Award for Distinguished Young Scientist, 1997
  • The Croucher Foundation Lectureship at Hong Kong Baptist University, 1998
  • ※Creative Award on Organic Synthesis§ of Chinese Chemocal Society, Organic Chemistry Division, 2008

Professional Activities:

  • Council Member of the Chinese Chemical Society (2001-2006)
  • Member of the Organic Synthesis Division, Chinese Chemical Society (2001-)
  • Member of the Chemical Biology Division, Chinese Chemical Society (2007-)
  • Editorial Advisory Board of the Open Organic Chemistry Journal
  • Editorial board of 4 Chinese Journals:
      Science in China: Chemistry
      Youji Huaxue (Chinese Journal of Organic Chemistry);
      Natural Products Research & Development;
      J. of Xiamen Univ.
  • Secretary General, First Sino-France Symposium on Advanced Chemistry and its Applications, 2004, Xiamen, China
  • Secretary General, ICPC-17, 2007, Xiamen, China
  • Co-Chairman, Sino-France (Lyon) Workshop on Chemistry, 2007, Xiamen, China

Research Interests:

  • Organic synthesis; - Asymmetric synthesis;
  • Asymmetric synthesis of natural products and drugs (alkaloids, pheromones, etc).

EditedTextbook/ Book:

  • Huang, P.-Q.; Jin, L.-R.; Chen, A.-Q. Organic Synthesis, High education Press, Beijing: 2004.
  • Huang, Pei-Qiang ed., ※Organic Named Reactions, Reagents and Rules§ Chemical Industry Press, Beijing: 2008.

Contributed Chapters:

  • P.-Q. Huang, ※Asymmetric Synthesis of Five-Membered Ring Heterocycles§ in ※Asymmetric Synthesis of Nitrogen Heterocycles§ (J. Royer Ed.; H. P. Husson, Foreworded) Weinheim, Wiley-VCH, 2009.
  • Huang, Pei-Qiang, ※Asymmetric Synthesis of Alkaloids and related drugs§ in Chiral Synthesis and Chiral Drugs, Lin G-Q, et al edited, Chemical Industry Press, Beijing: 2008..
  • P.-Q. Huang, ※Recent Advances on the Asymmetric Synthesis of Bioactive 2-Pyrrolidinone-related Compounds Starting from Enantiomeric Malic Acid§ in New Methods for the Asymmetric Synthesis of Nitrogen Heterocycles, J. L. Vicario; D. Badia and L. Carrillo Ed. Research Signpost: Kerala, 2005, pp 197-222.
  • Huang, Pei-Qiang, ※Recent Progress in the Synthesis of Alkaloids§ in Progress in Natural Products, De-Quan Yu and Yu-Lin Wu, edited, Chemical Industry Press, Beijing: 2005, pp.599-634.
  • Huang, Pei-Qiang ※Modern Organic Synthesis§ in Strategies in the Development of Organic Synthesis in the 21th Century, Du, C.-P.; Liu, L.-S.; Zhang, H. edited, Chemical Industry Press, Beijing: 2002, pp.57-79.
  • Huang, Pei-Qiang ※Asymmetric Cycloadditions§ in Asymmetric Synthesis and Catalysis (in Chinese), Yang, D.-K.; et al edited, Foundation for Cultural and Education of Chung-Xin University, Taichung: 1998, pp.57-87.

Selected Publication of Prof. P. Q. Huang*s Group

  • Pei-Qiang Huang, Asymmetric Synthesis of Hydroxylated Pyrrolidines, Piperidines And Related Bioactive Compounds: from N-Acyliminium Chemistry to N-?-Carbanion Chemistry, Synlett 2006, 1133-1147. (Account)
  • Jie-Min Luo, Chao-Feng Dai, and Pei-Qiang Huang Asymmetric Syntheses and Wnt Signal Inhibitory Activity of Melleumin A and Four Analogues of Melleumins A, B Chem. Asian J. 2009, 4 (2), 328 每 335.
  • Li-Jiao Jiang, Hong-Qiao Lan, Jian-Feng Zheng,* Jian-Liang Ye, and Pei-Qiang Huang,* A Flexible Approach to Methyl (5S)-5-Alkyltetramate Derivatives, Synlett 2009, 297-301.
  • Wen Chen, Xiao Zheng, Yuan Ping Ruan, and Pei Qiang Huang,* Facile Syntheses of Three Ahp-type Building Blocks with Complementary Reactivity, Heterocycles 2009, 79,
  • Z. Wei, H.-Q. Lan, J.-F. Zheng, and P.-Q. Huang, ※A New and Concise Approach to (R)-?-Lipoic Acid§, Wei, Z.; Lan, H.-Q.; Zheng, J.-F. *; Huang P.-Q*. Synth. Comm. 2009, 39 (4), 691-701;
  • Chen, C. Y.; Zhou, Z. H,; Chen, H. B.; Huang, P. Q.; Tsai, K. R.; Chow, Y. L. Formations of mixed-valence oxovanadium (V,IV) citrates and homocitrate with N-heterocycle chelated ligand, Inorg. Chem. 2008, 47, 8714-8720..
  • Pei-Qiang Huang, Jie Meng, Gang Liu, Chen-Guo Feng, and Jie Chen, ※Asymmetric Syntheses of (-)-epi-Pseudoconhydrine and (?)-5-Hydroxysedamine Based on cis-Diastereoselective 1,4-Asymmetric Induction§, Tetrahedron: Asymmetry, 2008, 19 (11), 1297-1303.
  • Liang-Xian Liu, Qi-Long Peng, Pei-Qiang Huang, A new approach for the asymmetric synthesis of (2S,3S)-3-hydroxypipecolic acid, Tetrahedron: Asymmetry, 2008, 19 (10), 1200-1203.
  • Geng-Jie Lin, Shi-Peng Luo, Xiao Zheng, Jian-Liang Ye, and Pei-Qiang Huang,* Enantiodivergent Synthesis of trans-3,4-Disubstituted Succinimides by SmI2-Mediated Reformatsky Type Reaction, Tetrahedron Lett. 2008, 49 (25), 4007-4010.
  • Tian-Jun Wu, Pei-Qiang Huang*, A Concise Approach to (+)-1-Epi-castanospermine, Tetrahedron Lett. 2008, 49 (2), 383-386.
  • Xiang Zhou, Jian-Liang Ye and Pei-Qiang Huang*, "A Versatile Approach to (4S,5R)-4-Benzyloxy-5-([?-hydroxyalkyl)-2-pyrrolidinones:Experimental Evidences to the Computational Predictions", Comptes Rendus de l'Acad谷mie des Sciences 每 CHIMIE (Comptes Rendus每CHIMIE), 2008, 11, 5-18.
  • Jian-Feng Zheng, Wen Chen, Jian-Liang Ye, Su-Yu Huang and Pei-Qiang Huang,* ※A divergent asymmetric approach to aza-spiropyran derivative and (1S,8aR)-1-hydroxyindolizidine§, Beil. J. Org. Chem., 2007, 3:41, 1-5.
  • Xiang Zhou, Wen-Jun Liu, Jian-Liang Ye and Pei-Qiang Huang, "Complementary Stereocontrolled Approaches to 2-Pyrrolidinones Bearing Vicinal Amino Diol Subunit with Three Continuous Chiral Centers: A Formal Asymmetric Synthesis of (?)-Detoxinine", J. Org. Chem., 2007, 72 (23), 8904-8909.
  • Chao-Feng Dai, Fang Cheng, Hai-Chao Xu, Yuan-Ping Ruan,and Pei-Qiang Huang, "Diversity-Oriented Asymmetric Synthesis of Hapalosin: Construction of Three Small C-9/ C-4/ C-3-Modified Hapalosin Analogues Libraries" J. Comb. Chem. 2007, 9 (3), 386-394.
  • Jian-Liang Ye, Pei-Qiang Huang*, Xin Lu*, Mechanism for the Regioselective Asymmetric Addition of Grignard, Reagents to Malimides: A Computational Exploration, J. Org. Chem., 2007, 72 (1), 35-42.
  • X. Zhou, W.-J. Liu; J.-L. Ye, and P.-Q. Huang,* A Versatile Approach to Pyrrolidine Azasugars and Homoazasugars Based on a Highly Diastereoselective Reductive Benzyloxymethylation of Protected Tartarimide, Tetrahedron 2007, 50 (27), 6346-6357. (Invited)
  • Guo Chen,PaP Xiao Zheng,PaP and Pei-Qiang Huang,* A New Synthesis of alkaloid (S)-3-Hydroxypiperidin-2-one and Its O-TBS Protected Derivative, J. Heterocyclic Chem. 2007, 44 (2): 499-501.
  • Liang-Xian Liu, Pei-Qiang Huang,*P PSBNB2 Reaction of 2-Substituted 3-Piperidinol Mesylate with Retention of ConfigurationㄩApplication to the Asymmetric Synthesis of (2R,3S)-CP-99,994, Tetrahedron: Asymmetry 2006, 16 (23), 3265-3272.
  • Hong-Bin Chen, Ling-Yan Chen, Pei-Qiang Huang,* Hong-Kui, Zhang, Zhao-Hui Zhou, and Khi-Rui Tsai, Expeditious Biomimetically-Inspired Approaches to Racemic Homocitric Acid Lactone and Per-homocitrate, Tetrahedron Tetrahedron 2007, 63 (10), 2148-2152.
  • Chen-Guo Feng, Jie Chen, Jian-Liang Ye, Yuan-Ping Ruan, Xiao Zheng and Pei-Qiang Huang,* Syntheses of Enantio-enriched Chiral Building Blocks from L-Glutamic Acid, Tetrahedron 2006, 62 (31), 7459-7465.
  • Xiang Zhou and Pei-Qiang Huang,* A Versatile Approach to Protected (4S,5R)-4-Hydroxy-5-(?-hydroxyalkyl)-2-pyrrolidinones, Synlett, 2006, 1235-1239.
  • Pei-Qiang Huang,* Zheng-Qing Guo, and Yuan-Ping Ruan, A Versatile Approach for the Asymmetric Syntheses of (1R,9aR)-Epiquinamide and (1R,9aR)-Homopumiliotoxin 223G, Org. Lett. 2006, 8 (7), 1435-1438.
  • Bang-Guo Wei, Jie Chen, Pei-Qiang Huang ※A New Approach for the Asymmetric Syntheses of 2-epi-Deoxoprosopinine and Azasugar Derivatives§ Tetrahedron 2006, 62, 190-198.
  • Xiao Zheng, Chen-Guo Feng, P.-Q. Huang*, Samarium Diiodide Promoted Asymmetric ?-Amido- hydroxyalkylation of Protected 3-Hydroxy 2-carbanion Pyrrolidine, Org. Lett. 2005, 7 (4), 553-556.
  • P.-Q. Huang, Z.-Y. Li An Alternative Asymmetric Synthesis of (S)-Homocitric Acid Lactone Tetrahedron:Asymmetry, 2005, 16 (20), 3367-3370.
  • Yuan-Ping Ruan, Bang-Guo Wei, Xiu-Qing Xu, Gang Liu,P PDe-Sheng Yu,P PLiang-Xian Liu,P PPei-Qiang Huang ※Detailed Studies on the Enantioselective Synthesis and HPLC Enantioseparation of N-Protected 3-Hydroxyglutarimides§, Chirality 2005, 17, 595-599
  • Tian Tang, Yuan-Ping Ruan, Jian-Liang Ye, P.-Q. Huang*, A Flexible Carbanionic Approach to Protected trans-(2R,3S)-2-Substituted 3-Aminopyrrolidines: Application to the Asymmetric Synthesis of (+)-Absouline, Synlett, 2005, (2), 231-234.
  • M.-D. Chen, M.-Z. He, X. Zhou, L.-Q. Huang, Y.-P. Ruan,P.-Q. Huang*, Studies on the Diastereoselective Reductive Alkylation of (R)-Phenylglycinol Derived Phthalimide: Observation of Stereoelectronic effects, Tetrahedron, 2005, 60 (5), 1335-1344.
  • Jian-Feng Zheng, Li-Ren Jin and P.-Q. Huang,* Enantio-divergent Synthesis of Both Enantiomers of Marine Alkaloids Haliclorensin and Isohaliclorensin, Constituent of Halitulin, Org. Lett. 2004, 6 (7), 1139-1142;
  • P.-Q. Huang,* Hong-Qiao Lan, Xiao Zheng and Yuan-Ping Ruan, A Concise Asymmetric Synthesis of (2S,3S,7S)-3,7-Dimethylpentadecan-2-yl Acetate and Propionate, the Sex Pheromones of Pine Sawflies, J. Org. Chem., 2004, 69, 3964-3967;
  • TLiang-Xian Liu, Yuan-Ping Ruan, Zheng-Qing Guo, P.-Q. Huang*,TT A General Approach to (5S,6R)-6-Alkyl-5-benzyloxy-2-piperidinones: Application to the Asymmetric Syntheses of Neurokinin Substance P Receptor Antagonist (-)-L-733,061 and (-)-Deoxocassine, TJ. Org. Chem., 2004, 69 (18),T 6001每 6009;
  • P.-Q. Huang* and Jun Deng, A Flexible Approach For The Asymmetric Synthesis of N-Protected (R)-5-Alkyl tetramates and (R)-5-Alkyl tetramic Acid Derivatives, Synlett, 2004, (2), 247-250;
  • M.-D. Chen, M.-Z. He, X. Zhou, L.-Q. Huang, Y.-P. Ruan and P.-Q. Huang*, Studies on the Diastereoselective Reductive Alkylation of (R)-Phenylglycinol Derived Phthalimide: Observation of Stereoelectronic effects, Tetrahedron, 2004, 60(7), 1651-1657.
  • Jing-Xing Du, Hui-Ying Huang, P.-Q. Huang*ㄛA New Approach to Geissman-Waiss Lactone and The KeyIntermediate in the Synthesis of Pyrrolidine trans-Lactones, Tetrahedron: Asymmetry, 2004, 15 (21), 3461-3466;
  • W.-H. Meng, T. -J. Wu, H.-K. Zhang, P.-Q. Huang*, Asymmetric Syntheses of (2S,3S,4S)-3-Hydroxy-4-methylproline And 4*-t-Butoxyamido-2*-deoxythymidine, Tetrahedron: Asymmetry, 2004, 15(24), 3899-3910.
  • P.-Q. Huang,* W.-H. Meng, A New Approach to (2S,3S,4S)-3-Hydroxy-4- methylproline, A Subunit in Echinocandin B And Related Oligopeptide Antibiotics, TLett. Org. Chem., 2004, 1(1), 99-101.
  • Tian Tang, Chen Zhu, and P.-Q. Huang*, A Flexible Approach to (S)-3-Amino- 2-pyrrolidinone Derivatives, Heterocycles, 2004, 64, 121-128.
  • Y. P. Ruan, Ming-De Chen, Ming-Zhu He, Xiang Zhou, P.-Q. Huang*, A Practical Two-step Synthesis of 3-Alkyl-2,3-dihydro-1H-isoindolin-1-ones, Synth. Commun., 2004, 34(5), 853-861.
  • P.-Q. Huang,* Hui-Ying Huang, An Improved Asymmetric Synthesis of Unusual Amino Acid (2S, 3S)-3-Hydroxyproline, Synth. Commun., 2004, 34(8), 1377-1382;
  • C.-G. Feng, H. Fang and P.-Q. Huang, (2TST,3TST)-3-Hydroxy-1-(4-methoxybenzyl) piperidine-2-carboxamide, Acta Cryst. 2004. E60, o1075-o1077;
  • Jian-Liang Ye, Xu Tang and P.-Q. Huang*, Further studies on the reductive每alkylation of chiral endo-himimide derived from (R)-phenylglycinolㄛArkivoc, 2004, (ix) 34-43, at Hwww.arkat-usa.orgH;
  • Huang, P.-Q.*; Yu, X.Y.; Liu X.P. Asymmetric synthesis of ?,?-disubstituted ? -lactones, Acta Chim. Sinica 2004, 62 (18), 1794-1800 (in Chinese);
  • HRuan, Y.-PH.; HXu, X.-QH.; HHe, M.-ZH.; HZhou, XH.; HHuang, P.-QH* Chem. J. Chinese Universities 2004, 25 (6), 1031-1033 (in Chinese);
  • HRuan, Y.-PHH.; HAo, X.-PH.; HZhang; X.-MH.; Huang, P.-Q.* Liquid chromatographic resolution of enantiomeric 1,1 '-bi-2-naphthol and phenylsuccinic acid on a coated reversed-phase column with 2,6-O-butyled beta-cyclodextrins, Chinese J. Anal. Chem. 2004, 32 (7), 949-952 (in Chinese);
  • P.-Q. Huang,Tian-Jun Wu and Yuan-Ping Ruan, A Flexible Approach to (S)-5-Alkyl Tetramic Acid Derivatives: Application to the Asymmetric Synthesis of (+)-Preussin and Protected (3S,4S)-AHPPA, Org. Lett. 2003, 5 (23), 4341-4344;
  • P.-Q. Huang*ㄛL. X. Liu, B. -G. Wei, Y.-P. Ruan, Asymmetric Synthesis of (+)-L-733, 060 and (+)-CP-99, 994 Based on A New Chiral 3-Piperidinol Synthon, Org. Lett. 2003, 5 (11), 1927-1929;
  • Bi-Yan He, Tian -Jun Wu, Xian -Yong Yu, P.-Q. Huang*, A Flexible Non-amino acid-Based Formal Asymmetric Synthesis of Naturally Occurring (2R, 3S)-Aminotetradeca-5, 7-dien-3-ol: Observation of a Remarkable Protecting Group Effect. Tetrahedron:Asymmetry, 2003, 14 (14), 2101-2108;
  • P.-Q. Huang, Bang-Guo Wei, Yuan-Ping Ruan, Asymmetric Synthesis of Antimalarial Alkaloids (+)-Febrifugine and (+)-Isofebrifugine, Synlett, 2003, (11), 1663-1667;
  • P.-Q. Huang, X. Zheng, H. Wei, Synthesis of (S)-Vasicol and (S)-3-Hydroxy-2-pyrrolidinone, Heterocycles, 2003, 60 (8), 1833-1842;
  • Huang, P.-Q*.; Wu, Tian-Jun, Ye, Jian-Liang, A Flexible Approach to the ?-Amino-?-Hydroxy Acid Moiety of Hapalosin, Chin. J. Chem, 2003, 21 (7): 723-726;
  • P.-Q. HuangP?P, Xiao Zheng,, An Improved Formal Total Synthesis of (-)-Anisomycin, Arkivoc, 2003, (II), 7-14, at Hwww.arkat-usa.orgH;
  • Ye J.L., Wei Z.B., Chen Z, Huang P.-Q.* Synthesis and crystal structure of (1R, 2S, 5R, 8S, 9R, 10S)-8-methyl-4-aza-5-phenyl-7-oxatetracyclo[ (2,9).0 (4,8)]-11-en-3-one. Chin. J. Struct. Chem., 2003, 22 (2): 228-232;
  • Yu XY, Cai SH, Chen Z, Huang PQ, NMR and ESI-MS studies on the interactions between oxodiperoxooxalatovanadate and organic ligands, Acta Chim. Sinica, 2003, 61 (7): 994-999;
  • Jin LR*, Zheng JF, Huang SJ, Huang P.-Q. Preparation and characterization of chiral bis (oxazolinylpyridine) nickel (II) and iron (II) complexes, Chinese J. Inorg. Chem., 2003, (11), 1207-1211.
  • X. Zheng,P PP-Q Huang,P*P Y.-P. Ruan,P PA. W. M. Lee and W. H. Chan,P PA New Approach For Asymmetric Synthesis of (R)-3-Methylpyrrolidine Alkaloids from (S)-Malic AcidㄛNat. Prod. Lett., 2002, 16 (1), 53‵56;
  • M.每D Chen, M.-Z. He, L.-Q. Huang, Y.-P. Ruan, P.-Q. Huang*, A Versatile Approach for the Asymmetric Synthesis of 3-Alkyl-isoindolin-1-ones, Chin. J. Chem, 2002, 20 (11): 1149-1153;
  • Zhou XW, Ye JL, Chen Z*, Chen ZW, Huang P.-Q. Studies on the interactions between bioactive peroxovanadium complexes bearing organic ligands and histidine, Acta Chim. Sinica, 2002, 60 (5): 835-840;
  • P.-Q. Huang,*P P Xiao Zheng and Xian-Ming Deng, DIBAL-H-HNRB2B and DIBAL-H-HNRP1PRP2P.HCI complexes for efficient conversion of lactones and esters to amides, Tetrahedron Lett., 2001, 42 (51), 9039-9041;
  • Huang, P.-Q.* Progress on the asymmetric synthetic methodology based on malimide, Chin. J. Org. Chem. 2001, 21(11), 1065-1073 (in Chinese);
  • Ruan YP, Ao XP, Chen AQ, Huang P.-Q.*, Separation of 1,1*-binaphthalene-2,2 '-diol optical isomers by derivatization high performance liquid chromatography, Chin. J Anal. Chem., 2001, 29 (12), 1398-1401;
  • J. Lin, W. H. Chan*, A. W. M. Lee*, W. Y. Wong, P. Q. Huang, Asymmetric synthesis of 1,3- and 1,3,4-substituted pyrrolidines, Tetrahedron Lett., 2000, 41 (16), 2949-2951;
  • P.-Q. Huang*, Xu Tang, An Qi Chen, An Alternative Stereoselective Synthesis of Protected Trans-5-Alkyl-4-Hydroxy-2-Pyrrolidinones, Synth. Commun., 2000, 30(13), 2259-2268;
  • Hong Kui Zhang, Quan Feng Chen, P.-Q. Huang*, A versatile Approach to protected (S)-aspartimide, (4S)-amino-2-pyrrolidinone and (3S)-aminopyrrolidine from (S)-aspartic acid, Synth. Commun., 2000, 30(13), 2431-2444;
  • Huang, P.-Q*.; Lan, H.Q. Chen, M.D.; Zhang; H.K. Some observations on the asymmetric reductive alkylation of cyclic imides, Chin. J. Org. Chem. 2000, 20(5), 790-794 (in Chinese);
  • P.-Q. Huang,* X Zheng, S L Wang, J L Ye, LR Jin and Z. Chen, A New Approach to (S)-4-Hydroxy-2-pyrrolidinone And Its 3-Substituted Analogues, Tetrahedron: Asymmetry, 1999, 10 (17), 3309-3317;
  • P.-Q. Huang*, Quan Feng Chen, Chang Lin Chen and Hong Kui Zhang, Asymmetric Synthesis of (-)-(R)-Pyrrolam A Starting From (S)-Malic Acid, Tetrahedron: Asymmetry, 1999, 10 (19), 3827-3832;
  • Liren Jin*, Hong Wu, Huailing Wu, P.-Q. Huang, Kyeongeun Jung, Hong Lim, Enantioselective Synthesis of Pyrrolydinonyl Thymine Nucleoside Analogues, Chem. Lett., 1999, 687~688;
  • Liren Jin*, Jianliang Ye, Yong Xie, Jianghong Shi, P.-Q. Huang, Kyeongeun Jung, and Hong Lim, Asymmetric Synthesis of Polyhydroxy Nucleoside Analogues from Tartaric acid, Chinese Chem Lett., 1999, 10 (7), 543~546;
  • P.-Q. Huang*, Xiao Zheng, Shi Li Wang, Jian Liang YE, Li Ren JIN,A New Chiral Synthesis of Naturally Occurring (-)-(S)-4-Hydroxy-2-Pyrrolidinone, Chinese Chem. Lett., 1999, 10 (9), 735-736;
  • Huang, P.-Q*. D-Quinic acid, a versatile chiron in organic synthesis, Chinese J. Org. Chem. (in Chinese) 1999, 19(4), 364-373;
  • P. -Q. Huang*, S-L Wang, J-L Ye, Y-P Ruan, Y-Q Huang, H Zheng, J-X Gao, An Easy Access to Protected (4S, 5R)-5-Alkyl-4-hydroxy-2-pyrrolidinones and their Use as Versatile Synthetic Intermediates, Tetrahedron, 1998, 54(41), 12547-12560;
  • P.-Q. Huang*, S.-L. Wang, Y.-P Ruan, J.-X. Gao, A New Approach to (-)-Anisomycin, Nat. Prod. Lett., 1998, 11, 101‵106;
  • P.-Q. Huang*, J.-L. Ye, Z. Chen, Y.-P. Ruan, J.-X. Gao, A Versatile Approach to the Activated Form of (3S, 4R)-Statine And Its Analogues, Synth. Commun. 1998, 28 (3), 417‵426;
  • P.-Q. Huang*, Jing-Xing Gao, Green Chemistry: An Emerging Frontier, Progress in Chemistry, 1998, 10 (3), 265-272 (in Chinese);
  • P.-Q. Huang*, Shi-Li Wang, Hong Zheng, Xiang-Su Fei, First Asymmetric Synthesis of (2R,3R)-3-Amino-1-benzyl-2-methylpyrrolidine via A Highly Diastereroselective Reductive Alkylation, Tetrahedron Lett., 1997, 38(2), 271~272;
  • P.-Q. Huang*, Xiang Su Fei; H. Zheng, ?-Amidoalkylation Via Sulfones: Towards The Synthesis of Ant Venom Alkaloids, Chinese Chem. Lett., 1995, 6 (9), 739~742;
  • P.-Q. Huang*, Yuan-Ping Ruan, Synthesis of a chiral precursor for Preussin and AHPPA, Chem. J. Chinese Universities 1995, 16(12), 1914~1916 (in Chinese);
  • P.-Q. Huang; W. -S. Zhou*, Efficient Syntheses of A New Chiral Diene and A New Bridgehead Enone for A Diels-Alder Approach To Kaura-9(11),16-Dien-19-Oic Acid, Tetrahedron: Asymmetry, 1991, 2(9), 875~878;
  • P.-Q. Huang; W. S. Zhou*, An Improved Method For The Syntheses Of 弛-Substitued Cyclohexenones, Synth. Commun., 1991, 21(22), 2369~2376.
  • P.-Q. Huang; W. S. Zhou*, Synthesis of A Potential Antifeedant Sesquiterpene Intermediate From A New Terpenoid A, B-Ring Synthon By Tandem Michael Reaction, Chinese Chem. Lett., 1992, 3(10), 767~770.
  • P.-Q. Huang, K. Sabbe, M. Pottie, M. Vandewalle*, A Novel Synthesis of 19-Nor 1式,25-Dihydroxyvitamin DB3B And Related Analogues, Tetrahedron Lett., 1995, 36 (45), 8299~8302.
  • A. Diez, P.-Q.Huang, D.-S.Grierson, H.-P.Husson,* M. Rubiralta, Preparation Of A New Chiral 5,6-Dihydropyridinium Synthon, Heterocycles, 1990, 31(3), 485~492.
  • S.Arseniyadis, P.-Q. Huang, N. Morellet, J. C .Beloeil, H. -P. Husson*, On The 2, 4-Relative Stereochemistry of N-Substituted Oxazolidines Derived From Phenylglycinol, Heterocycles, 1990, 31(10), 1789~1799.
  • S. Arseniyadis, P. -Q. Huang, H. -P. Husson*, Synthesis of 2-Alkyl-Pyrrolidines: Towards Azabicyclic System, Tetrahedron Lett., 1988, 29(6), 631~634.
  • S. Arseniyadis, P. -Q. Huang And H. -P. Husson*, Short And Efficient Synthesis Of 3,5-Disubstituted Pyrrolizidine Alkaloids Via The CN(R, S) Method, Tetrahedron Lett., 1988, 29(12), 1391~1394.
  • S. Arseniyadis, P.-Q. Huang, D. Piveteau, H.-P. Husson*, Stereocontrolled Electrophilic-Nucleophilic 式,式'-Substitution of The Pyrrolidine Ring, Tetrahedron, 1988, 44(9), 2457~2470.
  • P. -Q. Huang, S. Arseniyadis, H.-P. Husson*, Chiral Pyrrolidine Synthon For A New Approach To The Synthesis of Alkaloids, Tetrahedron Lett. 1987, 28(5), 547~550.

Accomplished Targets (Total or Formal Total Synthesis)ㄩ