Eric Meggers

最新更新日期:2018-9-29 19:13:27     浏览次数:26751次     



学士 (德国Bonn大学,1995) ;
博士 (瑞士Basel大学,1999) ;
博士后 (美国Scripps研究所,1999-2002);
Assistant Professor (美国Pennsylvania大学,2002-2007);
W3 Professor (德国Marburg大学,2007-Now);
特聘教授 (厦门大学,2011-Now);

有机不对称催化, 可见光催化,金属有机物及配合物的化学生物学。

1. Aerobic Asymmetric Dehydrogenative Cross-Coupling between Two C sp3-H Groups Catalyzed by a Chiral-at-Metal Rhodium Complex,  Y. Tan, W. Yuan, L. Gong*, E. Meggers*, Angew. Chem. Int. Ed., 2015, 54, DOI: 10.1002/anie.201506273
2. Asymmetric Lewis acid catalysis directed by octahedral rhodium centrochirality, C. Wang, L.-A. Chen, H. Huo, X. Shen, K. Harms, L. Gong, E. Meggers*, Chem. Sci. 2015, 5, 1093.
3. Asymmetric photoredox transition-metal catalysis activated by visible light, H. Huo, X. Shen, C. Wang, L. Zhang, P. Rose, L.-A. Chen, K. Harms, M. Marsch, G. Hilt, E. Meggers*, Nature, 2014, 515, 100.
4. Metal-Templated Chiral Bronsted Base “Organocatalysis”, J. Ma, X. Ding, Y. Hu, Y. Huang, L. Gong*, E. Meggers*, Nature Commun. 2014, 5, 5531.
5. Asymmetric Catalysis Mediated by the Ligand Sphere of Ocatahedral Chiral-at-Metal Complexes, L. Gong*, L.-A.Chen, E. Meggers*, Angew. Chem. Int. Ed., 2014, 53, 10868.
6. Chiral-at-Metal Octahedral Iridium Catalyst for the Asymmetric Construction of an All-Carbon Quaternary Stereocenter, L.-A. Chen, X. Tang, J. Xi, W. Xu, L. Gong*, E. Meggers*, Angew. Chem. Int. Ed., 2013, 52, 14271.
7. Chiral Enol Oxazolines and Thiazolines as Auxiliary Ligands for the Asymmetric Synthesis of Ruthenium Polypyridyl Complexes, B. Huang, L. Wang, L. Gong*, E. Meggers*, Chem. Asian J. 2013, 8, 2274.
8. Chiral-Auxiliary-Mediated Asymmetric Synthesis of Ruthenium Polypyridyl Complexes, L. Gong, M. Wenzel, E. Meggers* , Acc. Chem. Res. 2013, 46,2645.
9. Asymmetric Catalysis with Inert Chiral-At-Metal Iridium Complex, L.-A. Chen, W. Xu, B. Huang, J. Ma, L. Wang, J. Xi, K. Harms, L. Gong*, E. Meggers*,  J. Am. Chem. Soc. 2013, 135,10592.
10. Thioether-Based Anchimeric Assistance for Asymmetric Coordination Chemistry with Ruthenium(II) and Osmium(II), L.-A. Chen, X. Ding, L. Gong*,  E. Meggers*,  Dalton Trans. 2013, 42, 5623.
11. Active versus Passive Substituent Participation in the Auxiliary-Mediated Asymmetric Synthesis of an Octahedral Metal Complex, L.-A. Chen, J. Ma, M. A. Celik, H.-L. Yu, Z. Cao, G. Frenking, L. Gong*, E. Meggers* , Chem. Asian J. 2012, 7, 2523.
12. Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors, L. Feng, Y. Geisselbrecht, S. Blanck, A. Wilbuer, G. E. Atilla-Gokcumen, P. Filippakopoulos, K. Kraling, M. A. Celik, K. Harms, J. Maksimoska, R. Marmorstein, G. Frenking, S. Knapp, L.-O. Essen, E. Meggers*, J. Am. Chem. Soc. 2011, 133, 5976.
13. From Conventional to Unusual Enzyme Inhibitor Scaffolds: The Ongoing Quest for Target Specificity, E. Meggers*, Angew. Chem. Int. Ed. 2011, 50, 2442.
14. Isomerization-Induced Asymmetric Coordination Chemistry: From Auxiliary Control to Asymmetric Catalysis, L. Gong, Z. Lin, K. Harms, E. Meggers*, Angew. Chem. Int. Ed. 2010, 49, 7955.
15. Synthesis and Properties of the Simplified Nucleic Acid GNA”, E. Meggers, L. Zhang, Acc. Chem. Res. 2010, 43, 1092.
16. Iridium Complex with Antiangiogenic Properties, A. Wilbuer, D. H. Vlecken, D. J. Schmitz, K. Kraling, K. Harms, C. P. Bagowski, E. Meggers*, Angew. Chem. Int. Ed. 2010, 49, 3839.
17. Chiral-Auxiliary-Mediated Asymmetric Synthesis of Tris-Heteroleptic Ruthenium Polypyridyl Complexes, L. Gong, S. P. Mulcahy, K. Harms, E. Meggers*, J. Am. Chem. Soc. 2009, 131, 9602.
18. Insight into the High Duplex Stability of the Simplified Nucleic Acid GNA, M. Schlegel, X. Xie, L. Zhang, E. Meggers*, Angew. Chem. Int. Ed. 2009, 48, 960.
19. Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes, J. Maksimoska, L. Feng, K. Harms, C. Yi, J. Kissil, R. Marmorstein, E. Meggers*, J. Am. Chem. Soc. 2008, 130, 15764.

Selected Topics of Current Interest
1.Asymmetric catalysis with chiral metal complexes

2.Chemical biology and medicinal chemistry with inert metal complexes

3.Asymmetric synthesis of metal complexes: From auxiliary mediation to asymmetric catalysis