叶龙武

最新更新日期:2017-2-11 22:06:52     浏览次数:13862次     
教授、博士生导师
电话:0592-2185833
电子邮箱:longwuye@xmu.edu.cn
课题组网站:http://chem.xmu.edu.cn/group/lwye/index.html
更新个人信息
个人简历:
博士后 (University of California at Santa Barbara,2009/05-2011/07)
博士后 (The Scripps Research Institute,2008/09-2009/05)
博士 (中科院上海有机所,2003/09-2008/07)
学士 (浙江大学化学系,1999/09-2003/07)

荣誉与获奖:
中科院院长优秀奖 (2008)
中科院优秀毕业生 (2008)
上海市自然科学一等奖 (2011)
福建省杰出青年科学基金 (2015)
Thieme Chemistry Journals Award (2016)
国家自然科学基金“优秀青年基金" (2016)
研究兴趣:
有机合成方法学:过渡金属催化的选择性控制与多样性合成; 功能分子全合成:生物活性分子、天然产物以及药物的合成。
近期主要代表论著:

24. B. Zhou, L. Li, X.-Q. Zhu, J.-Z. Yan, Y.-L. Guo, L.-W. Ye*, Yttrium-Catalyzed Tandem Intramolecular Hydroalkoxylation/Claisen Rearrangement: Efficient Synthesis of Medium-Sized Lactams, Angew. Chem. Int. Ed. 2017, 56, in press.

23. W.-B. Shen,† X.-Y. Xiao,† Q. Sun, B. Zhou, X.-Q. Zhu, J.-Z. Yan, X. Lu,* L.-W. Ye*, (†Shen and Xiao have an equal contribution to this paper) Highly Site-Selective Formal [5+2] and [4+2] Annulations of Isoxazoles with Heterosubstituted Alkynes by Platinum Catalysis: Rapid Access to Functionalized 1,3-Oxazepines and 2,5-Dihydropyridines, Angew. Chem. Int. Ed. 2017, 56, 605.

22. F. Pan,† X.-L. Li,† X.-M. Chen, C. Shu, P.-P. Ruan, C.-H. Shen, X. Lu,* L.-W. Ye*, (†Pan and Li have an equal contribution to this paper) Catalytic Ynamide Oxidation Strategy for the Preparation of α-Functionalized Amides, ACS Catal. 2016, 6, 6055.

21. Y.-F. Yu, C. Shu, T.-D. Tan, L. Li, S. Rafique, L.-W. Ye,* Synthesis of Enantioenriched Pyrrolidines via Gold-Catalyzed Tandem Cycloisomerization/Hydrogenation of Chiral Homopropargyl Sulfonamides, Org. Lett. 2016, 18, 5178. (Highlighted by: Synfacts, 2017, 13, 51)

20. C. Shu, C.-H. Shen, Y.-H. Wang, L. Li, T. Li, X. Lu,* L.-W. Ye,* Synthesis of 2-Aza-1,3-butadienes through Gold-Catalyzed Intermolecular Ynamide Amination/C-H Functionalization, Org. Lett. 2016, 18, 4630.

19. C. Shu, Y.-H. Wang, C.-H. Shen, P.-P. Ruan, X. Lu,* L.-W. Ye,* Gold-Catalyzed Intermolecular Ynamide Amination-Initiated Aza-Nazarov Cyclization: Access to Functionalized 2-Aminopyrroles, Org. Lett. 2016, 18, 3254.

18. C. Shu, L. Li, C.-H. Shen, P.-P. Ruan, C.-Y. Liu, L.-W. Ye,* Gold-Catalyzed Tandem Cycloisomerization/Halogenation of Chiral Homopropargyl Sulfonamides, Chem. Eur. J. 2016, 22, 2282. (selected as a frontispiece and hot paper)

17. C. Shu, Y.-H. Wang, B. Zhou, X.-L. Li, Y.-F. Ping, X. Lu,* L.-W. Ye,* Generation of α-Imino Gold Carbenes through Gold-Catalyzed Intermolecular Reaction of Azides with Ynamides, J. Am. Chem. Soc. 2015, 137, 9567. (Highlighted by JACS Homepage)

16. L. Li,† B. Zhou,† Y.-H. Wang, C. Shu, Y.-F. Pan, X. Lu,* L.-W. Ye,* (†Li and Zhou have an equal contribution to this paper) Zinc-Catalyzed Tandem Alkyne Oxidation/C−H Functionalization: Highly Site-Selective Synthesis of Versatile Isoquinolones and β-Carbolines, Angew. Chem. Int. Ed. 2015, 54, 8245. (Featured in Chin. J. Org. Chem. 2015, 35, 2019 & invited as SYNPACTS article)

15. A.-H. Zhou, Q. He, C. Shu, Y.-F. Yu, S. Liu, T. Zhao, W. Zhang, X. Lu,* L.-W. Ye,* Atom-Economic Generation of Gold Carbenes: Gold-Catalyzed Formal [3+2] Cycloaddition between Ynamides and Isoxazoles, Chem. Sci. 2015, 6, 1265.

14. Y.-F. Yu, C. Shu, B. Zhou, J.-Q. Li, J.-M. Zhou, L.-W. Ye,* Efficient and Practical Synthesis of Enantioenriched 2,3-Dihydropyrroles through Gold-Catalyzed Anti-Markovnikov Hydroamination of Chiral Homopropargyl Sulfonamides, Chem. Commun. 2015, 51, 2126. (Highlighted by: Organic Chemistry Portal)

13. A.-H. Zhou, F. Pan, C. Zhu,* L.-W. Ye,* Recent Progress towards Transition Metal-Catalyzed Synthesis of Fluorenes, Chem. Eur. J. 2015, 21, 10278. (invited review paper)

12. L. Li,† C. Shu,† B. Zhou, Y.-F. Yu, X.-Y. Xiao, L.-W. Ye,* (†Li and Shu have an equal contribution to this paper) Generation of Gold Carbenes in Water: Efficient Intermolecular Trapping of the α-Oxo Gold Carbenoids by Indoles and Anilines, Chem. Sci. 2014, 5, 4057.

11. F. Pan, S. Liu, C. Shu, R.-K. Lin, Y.-F. Yu, J.-M. Zhou, L.-W. Ye,* Gold-Catalyzed Intermolecular Oxidation of o-Alkynylbiaryls: An Easy and Practical Access to Functionalized Fluorenes, Chem. Commun. 2014, 50, 10726.

10. C. Shu, L. Li, X.-Y. Xiao, Y.-F. Yu, Y.-F. Ping, J.-M. Zhou, L.-W. Ye,* Flexible and Practical Synthesis of 3-Oxyindoles through Gold-Catalyzed Intermolecular Oxidation of o-Ethynylanilines, Chem. Commun. 2014, 50, 8689.

9. C. Shu, L. Li, Y.-F. Yu, S. Jiang, L.-W. Ye,* Gold-Catalyzed Intermolecular Oxidation of Chiral Homopropargyl Sulfonamides: A Reliable Access to Enantioenriched Pyrrolidin-3-ones, Chem. Commun. 2014, 50, 2522.

8. C. Shu, C.-B. Chen, W.-X. Chen, L.-W. Ye,* Flexible and Practical Synthesis of Anthracenes through Gold-Catalyzed Cyclization of o-Alkynyldiarylmethanes, Org. Lett. 2013, 15, 5542. (Highlighted by: Synfacts, 2014, 10, 30)

7. C. Shu, M.-Q. Liu, Y.-Z. Sun, L.-W. Ye,* Efficient Synthesis of γ-Lactones via Gold-Catalyzed Tandem Cycloisomerization/Oxidation, Org. Lett. 2012, 14, 4958. (Highlighted by: Organic Chemistry Portal)

6. L. Ye, Y. Wang, D. Aue, L. Zhang,* Experimental and Computational Evidence for Gold Vinylidenes: Generation from Terminal Alkynes via a Bifurcation Pathway and Facile C−H Insertions, J. Am. Chem. Soc. 2012, 134, 31.

5. L. Ye, W. He, L. Zhang,* A Flexible and Stereoselective Synthesis of Azetidine-3-one via A Key Gold-Catalyzed Intermolecular Alkyne Oxidation, Angew. Chem. Int. Ed. 2011, 50, 3236. (For a highlight, see: Synfacts, 2011, 6, 630)

4. L. Ye, W. He, L. Zhang,* Gold-Catalyzed One-Step Practical Synthesis of Oxetan-3-ones from Readily Available Propargylic Alcohols, J. Am. Chem. Soc. 2010, 132, 8550.

3. L. Ye, L. Cui, G. Zhang, L. Zhang,* Alkynes as Equivalents of α-Diazo Ketones in Generating α-Oxo Metal Carbenes: A Gold-Catalyzed Expedient Synthesis of Dihydrofuran-3-ones, J. Am. Chem. Soc. 2010, 132, 3258.

2. L.-W. Ye, J. Zhou, Y. Tang,* Phosphine-Triggered Synthesis of Functionalized Cyclic Compounds, Chem. Soc. Rev. 2008, 37, 1140.

1. L.-W. Ye, X.-L. Sun, Q.-G. Wang, Y. Tang,* Phosphine-Catalyzed Intramolecular Formal [3+2] Cycloaddition for Highly Diastereoselective Synthesis of Bicyclo[n.3.0] Compounds, Angew. Chem. Int. Ed. 2007, 46, 5951. (For a highlight, see: Synfacts, 2007, 10, 1101)


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