詹庄平

最新更新日期:2015-4-24 10:08:39     浏览次数:8505次     
教授、博士生导师
电话:(0592)2180318 (办公室)
   (0592)2187195 (实验室)
电子邮箱:zpzhan@xmu.edu.cn

课题组网站:http://chem-zzp.xmu.edu.cn/
更新个人信息
个人简历:
博士(浙江大学,1998)
硕士(南开大学,1991)
学士(浙江大学,1985)
博士后(台湾清华大学,美国Johns Hopkins University)
研究兴趣:
有机合成:基于炔丙醇为原料的杂环化合物新合成方法研究; 药物合成:应用新合成方法合成药物和天然化合物; 香料合成:天然香料的研发
近期主要代表论著:



2015

1. Synthesis of 5,6-Dihydropyrazolo[1,5c]quinazolines through Gold-Catalyzed ChemoselectiveBicyclization of NPropargylic Sulfonylhydrazones.Hai-Tao Tang, Kai Xiong, Ren-Hao Li, Zong-Cang Ding, and Zhuang-Ping Zhan*, Org. Lett.2015, 17, 326-329.

2014

2. Synthesis of Polysubstituted Pyrazoles by aPlatinum-Catalyzed Sigmatropic Rearrangement/Cyclization Cascade. Jia-Jie Wen,Hai-Tao Tang, Kai Xiong, Zong-Cang Ding, and Zhuang-Ping Zhan*, Org. Lett.2014, 16, 5940−5943.

3. Base-Catalyzed N_N Bond Cleavage of Hydrazones:Synthesis of a-AminoKetones. Hai-Tao Tang, Yun-Bing Zhou, Yu Zhu, Hong-ChaoSun, Min Lin, and Zhuang-Ping Zhan*,Chem. Asian J. 2014, 9, 1278 -1281.

4. Selective synthesis of 4-(sulfonyl)-methyl-1Hpyrazolesand (E)-4,5-dihydro-1H-pyrazoles from N-allenic sulfonylhydrazones. Yu Zhu, Jun-JieHong, Yun-Bin Zhou, Yu-Wei Xiao, Min Lin and Zhuang-Ping Zhan*,Org.Biomol. Chem. 2014, 12, 3797–3801.

5. Silver(I)-catalyzed annulation for the regioselectivesynthesis of N-imino-γ-carbolinium ylides from hydrazones of indole-3-carbonylderivatives and propargylic alcohols. Yu Zhu, Xin-Rui Shen, Hai-Tao Tang, MinLin and Zhuang-Ping Zhan*, Org. Biomol. Chem. 2014, 12, 9514-9518.

2013

6. Lewis Base Catalyzed Synthesis of Multisubstituted4-Sulfonyl-1 H-Pyrazole Involving a Novel 1, 3-Sulfonyl Shift. Yu Zhu, Wen-TingLu, Hong-Cao Sun, Zhuang-Ping Zhan*Org.Lett. 2013, 15,4146-4149.

7. Copper (I)-Catalyzed Stereoselective Synthesis of(1E,3E)-2-Sulfonyl-1,3-dienes from N-Propargylic Sulfonohydrazones. Yu Zhu, Hai-Tao Tang, Zhuang-Ping Zhan*, Adv. Synth. Catal.2013,355, 1291-1296.

8. One-Pot Synthesis of Pyrazoles through a Four-StepCascade Sequence.Lu Hao, Junjie Hong, Jun Zhu, Zhuang-Ping Zhan*Chem.Eur. J.2013, 19, 5715-5720.

9.Chemoselective synthesis of substituted pyrazolesthrough AgOTf-catalyzed cascade propargylicsubstitution-cyclization-aromatization. Su-Xia Xu, Lu Hao, Tao Wang,Zong-Cang Ding, Zhuang-Ping Zhan*Org.Biomol. Chem.2013, 11, 294-298.

2012

10.Synthesis ofAcrylonitriles through an FeCl3-Catalyzed Domino Propargylic Substitution/Aza-Meyer–SchusterRearrangement Sequence. Lu Hao, Feng Wu, Zong-Cang Ding, Su-Xia Xu, Yan-Li Ma,Li Chen, and Zhuang-Ping Zhan*Chem. Eur. J.2012, 18, 6453–6456. 

11.The Synthesis of Aromatic Heterocycles from Propargylic Compounds. Wen Jia-Jie, Yu Zhu, Zhuang-Ping Zhan*, Asian J. Org. Chem., 2012,1, 108-129.(综述)

12. Microwave-assisted synthesis of2-aminopyrimidines from silica gel-adsorbed propargyl alcohols and guanidineFeng Wu, Zhuang-Ping Zhan*,Heterocycles 2012,85, 1891-1896.


2011

13. Atom-Economical Chemoselective Synthesis of 1,4-Diynesand Polysubstituted Furans/Pyrroles from Propargyl Alcohols and TerminalAlkynes. Tao Wang, Xin-liang Chen, Li Chen, and Zhuang-ping Zhan*,Org. Lett.2011, 13, 3324-3327.

14. Nucleophilic Substitution of SecondaryAlkyl-Substituted Propargyl Acetates: An Economic and Practical IndiumTrichloride Catalyzed Access. Min Lin , Lu Hao, Xiao-tao Liu, Qing-zhen Chen,Feng Wu, Ping Yan, Su-xia Xu, Xin-liang Chen, Jia-jie Wen, Zhuang-ping Zhan*, Synlett2011,665-670.

15. Copper(II)-Catalyzed Synthesis of Pyrimidines fromPropargylic Alcohols and Amidine: A Propargylation–Cyclization–Oxidation TandemReaction. Min Lin, Qing-zhen Chen, Yu Zhu, Xin-liang Chen, Ji-jun Cai,Ying-ming Pan,Zhuang-ping Zhan*,Synlett2011, 1179-1183.

16. The Construction ofFive-Membered Heterocycles by Transition Metal-Catalyzed Cyclization ofPropargylic Compounds.Lu Hao and Zhuang-Ping Zhan*, Current Organic Chemistry2011, 15, 1625-1643(综述)

2010

16. Chemoselective Cascade Synthesis of N-FusedHeterocycles via Silver(I) Triflate-Catalyzed Friedel–Crafts/N-C Bond FormationSequence. Lu Hao, Yingming Pan, Tao Wang, Min Lin, Li Chen, Zhuang-ping Zhan*,Adv. Synth. Catal.,2010, 352, 3215-3222.

17. Solvent-Free Solid Acid-Catalyzed NucleophilicSubstitution of Propargylic Alcohols: A Green Approach for the Synthesis of 1,4-diynes. Tao Wang, Rui-da Ma and Zhuang-ping Zhan*, Green Chem. 2010, 12, 1576–1579.

18. Facile one-pot synthesis of three differentsubstituted thiazoles from propargylic alcohols. Xun Gao, Ying-ming Pan, MinLin, Li Chen and Zhuang-ping Zhan*. Org. Biomol. Chem. 2010, 8, 3259–3266. ( highlightedby Synfacts,Synfacts, 2010, 9, 996)

19. One-pot highly efficient synthesis of substitutedpyrroles and N-bridgehead pyrroles by zinc-catalyzed multicomponent reaction. Xiao-taoLiu, Lu Hao, Min Lin, Li Chen and Zhuang-pingZhan*. Org. Biomol. Chem. 2010, 8, 3064–3072.

2009

19. Brønsted Acid-Catalyzed Propargylation/CycloisomerizationTandem Reaction: One-Pot Synthesis of Substituted Oxazoles from PropargylicAlcohols and Amides. Ying-ming Pan, Fei-jian Zheng, Hai-xin Lin, and Zhuang-ping Zhan*.J. Org. Chem. 2009, 74, 3148-3151.Impact factor: 4.6 (highlighted by Synfacts, Synfacts, 2009, 7, 724.)

20. A One-Pot Synthesis of Substituted Furans UsingCu(OTf)2-Catalyzed Propargylation/Cycloisomerization Tandem Reaction. Ying-mingPan, Su-yan Zhao, Wen-hua Ji and Zhuang-pingZhan*. J. Comb. Chem. 2009, 11, 103-109.

2008

21. Indium(III) Chloride CatalyzedPropargylation/Amination/Cycloisomerization Tandem Reaction: One-Pot Synthesisof Highly Substituted Pyrroles from Propargylic Alcohols, 1,3-DicarbonylCompounds and Primary Amines. Xiao-tao Liu, Lei Huang, Fei-jian Zheng, and Zhuang-ping Zhan*. Adv. Synth. Catal. 2008,350, 2778-2788. [highlighted by Synfacts,(Synfacts2009, 3, 249)]

22. FeCl3-CatalyzedPropargylation/Cycloisomerization Tandem Reaction: A Facile One-Pot Synthesisof Substituted Furans. Wen-hua Ji, Ying-ming Pan, Su-yan Zhao, Zhuang-ping Zhan*.Synlett. 2008,3046-3052.

2007

23Copper (II) triflateCatalyzed Nucleophilic Substitution of Propargylic Acetates with Enoxysilanes.A Straightforward Synthetic Routeto Polysubstituted Furans. Zhuang-pingZhan,* Shao-pei Wang, Xu-bin Cai, Hui-juan Liu, Jing-liang Yu and Yuan-yuanCui, Adv. Synth. Catal. 2007, 349, 2097-2102.

24. FeCl3-Catalyzed Nucleophilic Substitution ofPropargylic Acetates with Enoxysilanes.Zhuang-pingZhan,* Xu-bin Cai, Shao-pei Wang, Jing-liang Yu, Hui-juan Liu and Yuan-yuan Cui,J. Org. Chem.2007, 72, 9838-9841.

2006

25. BiCl3-Catalyzed propargylic substitution reactionof propargylic alcohols with C-, O-, S- and N-centered nucleophiles. Zhuang-Ping Zhan,*  Wen-zhen Yang,Rui-feng Yang, Jing-liang Yu, Jun-ping Li and Hui-juan Liu, Chem. Commun. 2006, 3352-3354.

26. A General and Efficient FeCl3–CatalyzedNucleophilic Substitution of Propargylic Alcohols.Zhuang-PingZhan,* Jing-liang Yu, Hui-juan LiuYuan-yuan Cui, Rui-fengYang, Wen-zhen Yang, and Jun-ping Li, J.Org. Chem.2006, 718298-8301.

27. FeCl3-CatalyzedCoupling of Propargylic Acetates with Alcohols. Zhuang-Ping Zhan,* Hui-JuanLiu, Synlett2006, 14, 2278.

28. FeCl3-CatalyzedPropargylation of Aromatic Compounds with Propargylic Acetates. Zhuang-Ping Zhan,*Yuan-Yuan Cui andHui-Juan Liu, Tetrahedron Letters, 2006,479143.

29. Bismuth Trichloride–Catalyzed C-Alkylation ofPyrroles with Electron-Deficient Olefins. Zhuang-PingZhan*, Jiang-Liang Yu, Wen-Zhen Yang, Synth. Commun. 2006, 36, 1373.

 


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