姚宏伟

最新更新日期:2016-11-11 11:39:29     浏览次数:630次     
更新个人信息
个人简历:
  1. 1999-2003 南京大学学士
  2. 2003-2009 中国科学院生物物理研究所博士
  3. 2009-2011 清华大学博士后
  4. 2011-2014 爱荷华州立大学博士后
  5. 2014-2016 麻省理工学院博士后
研究兴趣:
生物大分子的固体和液体核磁共振。
近期主要代表论著:

1.        H Yao, M Lee and M Hong, Solid-State NMR Investigation of the Structural Topology and Lipid Interactions of a Viral Fusion Protein Chimera Containing the Fusion Peptide and Transmembrane Domain.Biochemistry, 2016 (Accepted. DOI: 10.1021/acs.biochem.6b00568)

2.        H Yao, MW Lee, AJ Waring, GCL Wong and M Hong, Viral Fusion Protein Transmembrane Domain Adopts β-Strand Structure to Facilitate Membrane Topological Changes for Virus-Cell Fusion. Proc. Natl. Acad. Sci. USA, 2015, 112(35): 10926-10931.

3.        Y Yang, H Yao and M Hong, Distinguishing Bicontinuous Lipid Cubic Phases from Isotropic Membrane Morphologies Using 31P Solid-State NMR Spectroscopy. J. Phys. Chem. B, 2015, 119(15): 4993-5001.

4.        H Yao and M Hong, Conformation and lipid interaction of the fusion peptide of the Paramyxovirus PIV5 in anionic and negative-curvature membranes from solid-state NMR. J. Am. Chem. Soc., 2014, 136(6): 2611-2624.

5.        H Yao*, S Mi*, W Gong, N Xu, S Perrett, B Xia, J Wang and Y Feng, Anti-apoptosis proteins Mcl-1 and Bcl-xL have different p53-binding profiles. Biochemistry, 2013, 52(37): 6324-6334 (*equal authorship).

6.        H Yao and M Hong, Membrane-dependent conformation, dynamics, and lipid interactions of the fusion peptide of the paramyxovirus PIV5 from solid-state NMR. J. Mol. Biol., 2013, 425(3): 563-576.

7.        T Wang, H Yao and M Hong, Determining the depth of insertion of dynamically invisible membrane peptides by gel-phase 1H spin diffusion heteronuclear correlation NMR. J. Biomol. NMR, 2013, 56(2): 139-148.

8.        H Yao, Y Feng, T Zhou, J Wang and ZX Wang, NMR studies of the interaction between human programmed cell death 5 and human p53. Biochemistry, 2012, 51(13): 2684-2693.

9.        Y Liu, N Zhang, X Liu, X Wang, ZX Wang, Y Chen, H Yao, M Ge and X Pan, Molecular mechanism underlying the interaction of typical Sac10b family proteins with DNA. PLoS One, 2012, 7(4): e34986.

10.    H Yao, Y Feng and J Wang, Dimer Form of Archaeal Protein SSO6904 Identified by NMR. Chinese Journal of Magnetic Resonance, 2012, 29(2): 224-230.

11.    Y Liu, N Zhang, H Yao, X Pan and M Ge, Mth10b, a unique member of the Sac10b family, does not bind nucleic acid. PloS One, 2011, 6(5): e19977.

12.    Y Feng, H Yao and J Wang, Crystal structure of the crenarchaeal conserved chromatin protein Cren7 and double-stranded DNA complex. Protein Science, 2010, 19(6): 1253-1257.

13.    M Wang, Y Feng, H Yao and J Wang, Importance of the C-terminal loop L137-S141 for the folding and folding stability of staphylococcal nuclease. Biochemistry, 2010, 49(20): 4318-4326.

14.    Y Feng, H Yao and J Wang, Solution structure and calcium binding of protein SSO6904 from the hyperthermophilic archaeon Sulfolobussolfataricus. Proteins, 2010, 78(2): 474-479.

15.    H Yao*, L Xu*, Y Feng, D Liu, Y Chen and J Wang, Structure-function correlation of human programmed cell death 5 protein. Arch. Biochem. Biophys., 2009, 486(2): 141-149 (*equal authorship).

16.    J Xuan, H Yao, Y Feng and J Wang, Cloning, expression and purification of DNA-binding protein Mvo10b from Methanococcusvoltae. Protein Expr. Purif., 2009, 64(2): 162-166.

17.    L Guo, Y Feng, Z Zhang, H Yao, Y Luo, J Wang and L Huang, Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea. Nucleic Acids Res., 2008, 36(4): 1129-1137.

18.    Y Feng, D Liu, H Yao and J Wang, Solution structure and mapping of a very weak calcium-binding site of human translationally controlled tumor protein by NMR. Arch. Biochem. Biophys., 2007, 467(1): 48-57.

19.    D Liu*, H Yao*, Y Chen, Y Feng, Y Chen and J Wang, The N-terminal 26-residue fragment of human programmed cell death 5 protein can form a stable alpha-helix having unique electrostatic potential character. Biochem. J., 2005, 392(Pt 1): 47-54 (*equal authorship).

20.    Z Sun, J Chen, H Yao, L Liu, J Wang, J Zhang and JN Liu, Use of SspdnaB derived mini-intein as a fusion partner for production of recombinant human brain natriuretic peptide in Escherichia coli. Protein Expr. Purif., 2005, 43(1): 26-32.


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