吴川六

最新更新日期:2016-11-10 10:22:42     浏览次数:21740次     
课题组主页:http://chlwu.xmu.edu.cn
邮箱:chlwu@xmu.edu.cn
办公室:化学楼535
电话:0592-2183206
更新个人信息
个人简历:
博士(厦门大学,2005-2010)
学士(厦门大学,2001-2005)
研究助理(新加坡国立大学,2008-2009)
博士后(瑞士苏黎世联邦理工学院,2010-2012)

ETH Fellow(2010)
中组部第五批“青年千人”计划(2013)
研究兴趣:
多肽分子探针;荧光探针;多肽/蛋白递送系统;蛋白质–多肽分子相互作用;生物分子识别机制
近期主要代表论著:

1. Yunyang Ling, Jing Ren, Tao Li, Yibing Zhao and Chuanliu Wu*, POEGMA-Based Disulfide-Containing Fluorescent Probes for Imitating and Tracing Noninternalization-Based Intracellular Drug Delivery, Chem. Commun., 2016, 52, 4533−4536.
2. Yiwu Zheng, Linxiang Zhai, Yibing Zhao, and Chuanliu Wu*, Orthogonal Cysteine-Penicillamine Disulfide Pairing for Directing the Oxidative Folding of Peptides, J. Am. Chem. Soc., 2015, 137, 15094−15097.
3. Yujie Li, Tao Li, Jinghui Wang, Xiaojia Bao, Yibing Zhao, and Chuanliu Wu*, Multivalent Peptides Displayed on OEGMA-based Copolymers for the Modulation of Protein-Protein Interactions, Polym. Chem., 2015, 6, 7862−7870.
4. Yaqi Chen, Chaoqiong Yang, Tao Li, Miao Zhang, Yang Liu, Marc A. Gauthier, Yibing Zhao, and Chuanliu Wu*, The Interplay of Disulfide Bonds, α-Helicity, and Hydrophobic Interactions Leads to Ultrahigh Proteolytic Stability of Peptides, Biomacromolecules, 2015, 16, 2347−2355.
5. Linxiang Zhai, Jingjing Liang, Xiangqun Guo, Yibing Zhao, and Chuanliu Wu*, Extraordinary Modulation of Disulfide Redox-Responsiveness by Cooperativity of Twin-Disulfide Bonds, Chem. Eur. J., 2014, 20, 17507−17514.
6. Chuanliu Wu, Shuo Wang, Lorine Brülisauer, Jean-Christophe Leroux, and Marc A. Gauthier*, Broad Control of Disulfide Stability through Microenvironmental Effects and Analysis in Complex Redox Environments, Biomacromolecules, 2013, 14, 2383−2388.
7. Chuanliu Wu, Jean-Christophe Leroux,* and Marc A. Gauthier*, Twin Disulfides for Orthogonal Disulfide Pairing and the Directed Folding of Multicyclic Peptides, Nature Chem., 2012, 4, 1044−1049.
8. Chuanliu Wu, Cristina Belenda, Jean-Christophe Leroux, and Marc A. Gauthier*, Interplay of Chemical Microenvironment and Redox Environment on Thiol–Disulfide Exchange Kinetics, Chem. Eur. J., 2011, 17, 10064−10070.


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