Research Highlights

Research Highlights

[JACS] Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs

Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and DrugsAuthors: Shuaimin Lu, Shihui Fan, Shuling Xiao, Jingjing Li, Shilong Zhang, Yapei Wu, Chuilian Kong, Jie Zhuang, Hongtan Liu, Yibing Zhao, and Chuanliu Wu*Abstract: Multicyclic peptides with stable 3D structures are a kind...

[Nature Communication] Site- and enantioselective cross-coupling of saturated N-heterocycles with carboxylic acids by cooperative Ni/photoredox catalysis

Site- and enantioselective cross-coupling of saturated N-heterocycles with carboxylic acids by cooperative Ni/photoredox catalysisAuthors: Xiaomin Shu, De Zhong, Qian Huang, Leitao Huan, Haohua Huo*Abstract: Site- and enantioselective cross-coupling of saturated N-heterocycles and carboxylic acids—two of the most a...

[The Innovation] Upgrading heterogeneous Ni catalysts with thiol modification

Upgrading heterogeneous Ni catalysts with thiol modificationAuthors Pengpeng Ruan, Bili Chen, Qin Zhou, Hansong Zhang, Yahao Wang, Kunlong Liu, Wenting Zhou, Ruixuan Qin, Zhi Liu, Gang Fu*, Nanfeng Zheng*Abstract: Precious metal catalysts are the cornerstone of many industrial processes. Replacing precious metal cat...

[Nature Communication] Ampere-level current density ammonia electrochemical synthesis using CuCo nanosheets simulating nitrite reductase bifunctional nature

Ampere-level current density ammonia electrochemical synthesis using CuCo nanosheets simulating nitrite reductase bifunctional natureAuthors: Jia-yi Fang, Qi-Zheng Zheng, Yao-Lin Lou, Kuang-Min Zhao, Sheng-Nan Hu, Guang Li, Ouardia Akdim, Xiao-Yang Huang, and Shi-Gang Sun*Abstract: The development of electrocatalyst...

[Nature Communication] Deep transfer learning enables lesion tracing of circulating tumor cells

Deep transfer learning enables lesion tracing of circulating tumor cellsAuthors: Xiaoxu Guo, Fanghe Lin, Chuanyou Yi, Juan Song, Di Sun, Li Lin, Zhixiong Zhong, Zhaorun Wu, Xiaoyu Wang, Yingkun Zhang, Jin Li, Huimin Zhang*, Feng Liu*, Chaoyong Yang*, Jia Song*Abstract: Liquid biopsy offers great promise for noninvas...

[Nature Synthesis] Ring contraction of metallacyclobutadiene to metallacyclopropene driven by π- and σ-aromaticity relay

Ring contraction of metallacyclobutadiene to metallacyclopropene driven by π- and σ-aromaticity relayAuthors: Kaiyue Zhuo, Yanan Liu, Kaidong Ruan, Yuhui Hua, Yu-Mei Lin*, and Haiping Xia*Abstract: π-Aromaticity is an important driving force in directing the synthesis of aromatic compounds; in contrast, reactions...