Personal Profile:

Degrees:

Ph.D. (1996)     Quantum Chemistry, Xiamen University, Xiamen, Fujian, China

M.S. (1992)      Physics, Xiamen University, Xiamen, Fujian, China

B.S. (1986)       Physics, Xiamen University, Xiamen, Fujian, China

Educational and Professional Experiences:

Associate Professor:     Jul. 2009 – Present

Assistant Professor:  Sep. 1996 – Jun. 2009

Affiliation: Department,of Chemistry, Xiamen University, Fujian, China

Visiting Scholar： Mar. 2010 –Sep. 2011

Affiliation: Dr. Vitali Tugarinov’s laboratory，Department of Chemistry, University of Maryland, College Park, MD, USA

Funded by the China Scholarship Council

Ph.D. Student: Sep. 1992 – Sep. 1996

Affiliation: Department of Chemistry, Xiamen University,Fujian, China

Supervisor: Professor Qian’Er Zhang, CAS Member

Dissertation： ab initio Bonded Tableau Unitary Group Approach Studies on the Nature of the Chemical Bonding for Some Small Molecules

M.S. Student: Sep. 1989 – Sep. 1992

Affiliation:  Department of Physics, Xiamen University, Fujian, China

Supervisors: Professor Qinyi Wu

Thesis: Application of Computer Algebra REDUCE in Assisting NMR Pulse Sequence Analysis

Assistant Engineer: Jul. 1986 – Sep. 1989

Affiliation: Guangxi Electric Power Test Research Institute, Guangxi, China.

Job responsibilities:  Troubleshoot and repair electronic instruments

B.Sc. Student:  Sep. 1982 - Jul. 1986

   Affiliation: Department of Physics, Xiamen University, Xiamen, Fujian, China

Teaching courses:

• Basic Chemistry Experiments III - Instrumental Analysis

• Basic Chemistry Experiments III - Physical Chemistry Experiments

• Basic Chemistry Experiments I - Inorganic and Analytical Chemistry Experiments Preliminary statistical thermodynamics

• Advanced Instrumental Analysis - Spectroscopic Methods for Analyzing Small Molecule Structures

Research Interests:

• Characterize the structures of small molecules by using spectroscopic methods

• Analyze the structures of small molecules and biomolecules (proteins) by using spectroscopic methods.

Selected Recent Publications:

1. 1. Fan, Shihui; Zhuang, Jie; Guo, Chenyun; Lin, Donghai; Liao, Xinli*; H-1, C-13, N-15 backbone and side-chain chemical shift assignments of the polyketide cyclase from Mycobacterium tuberc ulosis, Biomolecular NMR Assignments, 15(2): 397-402. (2021)

2. 2. Huang, Lin; Liao, Xinli; Li, Mengxiao; Wang, Jia; Peng, Xuemei; Wilson, Timothy J.; Lille y, David M. J.; Structure and folding of four putative kink turns identified in structured RNA s pecies in a test of structural prediction rules, Nucleic Acids Research, 49(10): 5916-5924. (2021)

3. 3. Xinli Liao; Shaokuan Zheng; Guoxing Lin; Pulsed field gradient signal attenuation of res tricted anomalous diffusions in plate, sphere, and cylinder with wall relaxation, Physical Review E, 101(012128): 1-14 (2020)

4. 4. Biling Huang; Shihui Fan; Yan Liu; Yufen Zhao; Donghai Lin; Xinli Liao*; Solution structure and backbone dynamics for S1 domain of ribosomal protein S1 from Mycobacterium tuberculosis, European Biophysics Journal, 48(6): 491-501.(2019)

5. 5. Y. Fan, Y. Dai, M. Hou, H. Wang, H. Yao, C. Gu, D. Lin*, X. Liao*, Structural basis for ribosome protein S1 interaction with RNA in trans-translation of Mycobacterium tuberculosis. Biochem. Biophys. Resea. Commun. 487 268-273. (2017)

6. 6. J. Fu, B. Huang, D. Lin*, X.Liao* , Chemical shift assignments of Ribosomal protein S1 from Mycobacterium tuberculosis, Biomol NMR Assign 11:133–136.(2017)

7. 7. B. Huang, J. Fu, C. Guo, X.Wu, D. Lin, X.Liao*, ¹ H, ¹⁵N, ¹³C resonance assignments for pyrazinoic acid binding domain of ribosomal protein S1 from Mycobacterium tuberculosis,, Biomol NMR Assign 10:321–324. (2016).

8. 8. G. Lin, S. Zheng, X. Liao, Signal attenuation of PFG restricted anomalous diffusions in plate, sphere, and cylinder, J. Mag. Reson, 272 25–36. (2016)

9. 9. J. Yang, Y. Liu, J. Bi, Q. Cai, X. Liao, W. Li, C. Guo, Q. Zhang, T. Lin, Y. Zhao, H. Wang, J. Liu*, X. Zhang*, D. Lin*. Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide, Molecular Microbiology, DOI: 10.111/mmi.12892 (2014)

10. 10. Fu CP， Peng Y， Liao XL，Guo CY, Lin DH. H-1, C-13, N-15 backbone and side-chain resonance assignments of the human adenylate kinase 1 in apo form. Biomolecular NMR Assignments. Vol 7(2) 155-158 Oct. 2013

11. 11. Liao X, Long D, Li D, Bruschweiler R, Tugarinov V. Probing Side Chain Dynamics in Proteins by the Measurement of Nine Deuterium Relaxation Rates Per Methyl Group. J. Phys. Chem. B 116(1): 606-620 (2012).

12. 12. Liao X, Godoy-Ruiz R • Guo C, Tugarinov V. Simultaneous measurement of ¹H–¹⁵N and Methyl ¹Hm–¹³Cm residual dipolar couplings in large proteins. J Biomol NMR 51:191–198 (2011).

13. 13. Liao X, Tugarinov V, Selective detection of ¹³CHD2 signals from a mixture of ¹³CH3/¹³CH2D/¹³CHD2 methyl isotopomers in proteins, J. Magn. Reson. 209 (1): 101-107 (2011).

14. 14. Liao X, Jung P, Shuai J. Global Noise and Oscillations in Clustered Excitable Media. Physical Review E. 79 (4) 041923,1-6. (2009).

15. 15. Liao X, Chen X and Han D (2008). Interaction of Histidine with Metallic Ions Detected by ¹H-NMR. Journal of Xiamen University (Natural Science). 47: Sup1.55-58.