Personal Profile:
Degrees:
Ph.D. (1996) Quantum Chemistry, Xiamen University, Xiamen, Fujian, China
M.S. (1992) Physics, Xiamen University, Xiamen, Fujian, China
B.S. (1986) Physics, Xiamen University, Xiamen, Fujian, China
Educational and Professional Experiences:
Associate Professor: July. 2009- present
Affiliation: Department,of Chemistry, Xiamen University, Fujian, China
Visiting Scholar: Nov. 2023 - Jan. 2024
Affiliation: The University of Massachusetts, Chan Medical School, Worcester, MA, USA.
Research Interests: Anomalous diffusions
Visiting Scholar: Aug. 2019 - Oct. 2019
Affiliation: The University of Dundee, Dundee, UK.
Research Interests: Structure and folding of four putative kink turns RNA
Visiting Scholar: Apr. 2018 - June. 2018
Affiliation: The University of North Carolina at Chapel Hill, NC, USA.
Research Interests: Determining protein structure by NMR
Visiting Scholar: Mar. 2017 - April. 2017
Affiliation: The University of Massachusetts, Chan Medical School, Worcester, MA, USA.
Research Interests: Anomalous diffusions
Visiting Scholar: Aug. 2015 - Oct. 2015
Affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Research Interests: Determining protein structure by NMR
Visiting Scholar: Mar. 2010 - Sept. 2011
Affiliation: Department of Chemistry, University of Maryland, College Park, MD, USA.
Research Interests: Determining protein structure by NMR
Assistant Professor: Sept. 1996 – July. 2009
Affiliation: Department of Chemistry, Xiamen University, Fujian, China.
Research Interests: Determining small molecular structure by NMR
Ph.D. Student: Sept. 1992 – Sept. 1996
Affiliation: Department of Chemistry, Xiamen University, Fujian, China
Supervisor: Professor Qian’Er Zhang, CAS Member
Research Interests: Valence bond theory and its applications in chemical bonding features, structural chemistry
M.S. Student: Sept. 1989 – Sept. 1992
Affiliation: Department of Physics, Xiamen University,Fujian, China
Supervisors: Professor Qinyi Wu
Research Interests: REDUCE programming, Principles of NMR
Assistant Engineer: July 1986 – Sept. 1989
Affiliation: Guangxi Power Testing & Research Institute, Guangxi, China.
Research Interests: Instrument maintenance
B.Sc. Student: September 1982 - July 1986
Affiliation: Department of Physics, Xiamen University, Xiamen, Fujian, China
Research Interests:
Statistical thermodynamics：Statistical thermodynamics of equilibrium and non-equilibrium states
Determining molecular structures by NMR
Selected Recent Publications:
1. Fan, Shihui; Zhuang, Jie; Guo, Chenyun; Lin, Donghai; Liao, Xinli*; H-1, C-13, N-15 backbone and side-chain chemical shift assignments of the polyketide cyclase from Mycobacterium tuberc ulosis, Biomolecular NMR Assignments, 15(2): 397-402. (2021)
2. Huang, Lin; Liao, Xinli; Li, Mengxiao; Wang, Jia; Peng, Xuemei; Wilson, Timothy J.; Lille y, David M. J.; Structure and folding of four putative kink turns identified in structured RNA s pecies in a test of structural prediction rules, Nucleic Acids Research, 49(10): 5916-5924. (2021)
3. Xinli Liao; Shaokuan Zheng; Guoxing Lin; Pulsed field gradient signal attenuation of res tricted anomalous diffusions in plate, sphere, and cylinder with wall relaxation, Physical Review E, 101(012128): 1-14 (2020)
4. Biling Huang; Shihui Fan; Yan Liu; Yufen Zhao; Donghai Lin; Xinli Liao*; Solution structure and backbone dynamics for S1 domain of ribosomal protein S1 from Mycobacterium tuberculosis, European Biophysics Journal, 48(6): 491-501.(2019)
5. Y. Fan, Y. Dai, M. Hou, H. Wang, H. Yao, C. Gu, D. Lin*, X. Liao*, Structural basis for ribosome protein S1 interaction with RNA in trans-translation of Mycobacterium tuberculosis. Biochem. Biophys. Resea. Commun. 487 268-273. (2017)
6. J. Fu, B. Huang, D. Lin*, X.Liao* , Chemical shift assignments of Ribosomal protein S1 from Mycobacterium tuberculosis, Biomol NMR Assign 11:133–136.(2017)
7. B. Huang, J. Fu, C. Guo, X.Wu, D. Lin, X.Liao*, 1 H, 15N, 13C resonance assignments for pyrazinoic acid binding domain of ribosomal protein S1 from Mycobacterium tuberculosis,, Biomol NMR Assign 10:321–324. (2016).
8. G. Lin, S. Zheng, X. Liao, Signal attenuation of PFG restricted anomalous diffusions in plate, sphere, and cylinder, J. Mag. Reson, 272 25–36. (2016)
9. J. Yang, Y. Liu, J. Bi, Q. Cai, X. Liao, W. Li, C. Guo, Q. Zhang, T. Lin, Y. Zhao, H. Wang, J. Liu*, X. Zhang*, D. Lin*. Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide, Molecular Microbiology, DOI: 10.111/mmi.12892 (2014)
10. Fu CP， Peng Y， Liao XL，Guo CY, Lin DH. H-1, C-13, N-15 backbone and side-chain resonance assignments of the human adenylate kinase 1 in apo form. Biomolecular NMR Assignments. Vol 7(2) 155-158 Oct. 2013
11. Liao X, Long D, Li D, Bruschweiler R, Tugarinov V. Probing Side Chain Dynamics in Proteins by the Measurement of Nine Deuterium Relaxation Rates Per Methyl Group. J. Phys. Chem. B 116(1): 606-620 (2012).
12. Liao X, Godoy-Ruiz R • Guo C, Tugarinov V. Simultaneous measurement of 1H–15N and Methyl 1Hm–13Cm residual dipolar couplings in large proteins. J Biomol NMR 51:191–198 (2011).
13. Liao X, Tugarinov V, Selective detection of 13CHD2 signals from a mixture of 13CH3/13CH2D/13CHD2 methyl isotopomers in proteins, J. Magn. Reson. 209 (1): 101-107 (2011).
14. Liao X, Jung P, Shuai J. Global Noise and Oscillations in Clustered Excitable Media. Physical Review E. 79 (4) 041923,1-6. (2009).
15. Liao X, Chen X and Han D (2008). Interaction of Histidine with Metallic Ions Detected by 1H-NMR. Journal of Xiamen University (Natural Science). 47: Sup1.55-58.
