Title:    Novel approach for finding new chemical reactions and chemical information

Time:    2025-12-16 15:00

Lecturer:  Denis Chusov

Russian Academy of Sciences (INEOS RAS)

Venue:    Room 540, Chemistry Building

Abstract：

The discovery of novel chemical reactions attracts chemists both in academia and industry. Discovery can arise from either targeted design or unforeseen accident. However, in most cases an impulse towards the detailed investigation of the particular field is detection of an unexpected product in the chemical reaction. Herein, we report the possibility of searching for new chemical reactions by analyzing reaction mixtures using an artificial intelligence platform – OdanChem. This approach has high potential to accelerate the discovery of new reactions, and it shows advanced capabilities for (semi-)autonomous data analysis. Our results indicate that new reactions can be found even with simple chemical compounds, demonstrating the versatility and efficiency of this approach.

Bio of the Lecturer：

Prof. Denis Chusov is currently a Full Professor at the Nesmeyanov Institute, Russian Academy of Sciences (INEOS RAS). He is also the Head of the Laboratory of Effective Catalys at the Moscow Institute of Elementorganic Compounds, the Head of Department at HSE University, and a Laureate of the Moscow Government Prize. He defended his Ph.D. thesis under the supervision of Prof. Yuri N. Belokon at the Nesmeyanov Institute of Organoelement Compounds (Moscow). He then worked as a visiting researcher at Newcastle University (with Prof. Michael North) and at Université Paris-Sud 11 (with Prof. Henri Kagan). His postdoctoral studies were conducted at Max-Planck-Institut für Kohlenforschung (with Prof. Benjamin List). He has published more than 100 papers in journals including Angewndte Chemie, Nature Communications, ACS Catalysis, Chemical Science, Organic letters, etc. His approach of reductive amination without an external hydrogen source is using in Novartis company.