[Angew. Chem. Int. Ed.] Prof. Haichao XU & Prof. Xin LU's groups published a paper entitled "Electrochemical Synthesis of Imidazo‐Fused N‐Heteroaromatic Compounds through a C−N Bond‐Forming Radical Cascade"-College of Chemistry and Chemical Engineering

[Angew. Chem. Int. Ed.] Prof. Haichao XU & Prof. Xin LU's groups published a paper entitled "Electrochemical Synthesis of Imidazo‐Fused N‐Heteroaromatic Compounds through a C−N Bond‐Forming Radical Cascade"

Publish Date:17.April 2018 Visted: Times

Title: Electrochemical Synthesis of Imidazo‐Fused N‐Heteroaromatic Compounds through a C−N Bond‐Forming Radical Cascade

Author: Zhong‐Wei Hou Zhong‐Yi Mao Yared Yohannes Melcamu Prof. Dr. Xin Lu* Prof. Dr. Hai‐Chao Xu*

Summary:

We have developed a unified strategy for preparing a variety of imidazo‐fused N‐heteroaromatic compounds through regiospecific electrochemical (3+2) annulation reaction of heteroarylamines with tethered internal alkynes. The electrosynthesis employs a novel tetraarylhydrazine as the catalyst, has a broad substrate scope, and obviates the need for transition‐metal catalysts and oxidizing reagents.

Full Link: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201711876

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Research Highlights

[Angew. Chem. Int. Ed.] Prof. Haichao XU & Prof. Xin LU's groups published a paper entitled "Electrochemical Synthesis of Imidazo‐Fused N‐Heteroaromatic Compounds through a C−N Bond‐Forming Radical Cascade"