[Angew. Chem. Int. Ed.] Prof. Long-Wu Ye published a paper entitled “Yttrium-Catalyzed Intramolecular Hydroalkoxylation/Claisen Rearrangement Sequence: Efficient Synthesis of Medium-Sized Lactams”-College of Chemistry and Chemical Engineering

[Angew. Chem. Int. Ed.] Prof. Long-Wu Ye published a paper entitled “Yttrium-Catalyzed Intramolecular Hydroalkoxylation/Claisen Rearrangement Sequence: Efficient Synthesis of Medium-Sized Lactams”

Publish Date:10.March 2017 Visted: Times

Title: Yttrium-Catalyzed Intramolecular Hydroalkoxylation/Claisen Rearrangement Sequence: Efficient Synthesis of Medium-Sized Lactams

Author: Bo Zhou, Long Li, Xin-Qi Zhu, Juan-Zhu Yan, Yi-Lin Guo, Long-Wu Ye*

Abstract:
An efficient yttrium-catalyzed intramolecular hydroalkoxylation/Claisen rearrangement sequence has been achieved, thus enabling facile access to a diverse array of valuable medium-sized lactams. Furthermore, a mechanistic rationale for this novel cascade reaction is well supported by a variety of control experiments.

Full Link: http://onlinelibrary.wiley.com/doi/10.1002/anie.201700596/abstract

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Research Highlights

[Angew. Chem. Int. Ed.] Prof. Long-Wu Ye published a paper entitled “Yttrium-Catalyzed Intramolecular Hydroalkoxylation/Claisen Rearrangement Sequence: Efficient Synthesis of Medium-Sized Lactams”