Research Highlights

An Aptamer Cross-Linked Hydrogel as a Colorimetric

Publish Date:01.April 2010     Visted: Times       
An Aptamer Cross-Linked Hydrogel as a Colorimetric Platform for Visual Detection
 
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION ,Volume: 49  ,Issue: 6, Pages:1052-1056,Published: 2010
 
Author: Zhi Zhu, Cuichen Wu, Haipeng Liu, Yuan Zou, Xiaoling Zhang, Huaizhi Kang, Chaoyong James Yang,* and Weihong Tan*
 
Abstract:Cocaine cracked: The gel-sol transition of an enzyme-caged hydrogel has been efficiently controlled by target binding events, which trigger release of the enzyme to take part in its catalytic role for signal amplification (see picture). As low as 20 ng of cocaine can be visually detected within 10 min without any aid of sophisticated instrumentation.