Title: Fluorescent pyridine phosphonium salts via transmutation of metallabenzenes

Authors: Yaowei Zhang#, Feifei Han#, Zhihong Yin, Yapeng Cai, Xiaoyan Zhang, Hong Zhang*

Abstract: Metallabenzenes are recognized as a unique class of aromatic compounds, not only of structural and theoretical interest but also as platforms to design powerful transformations. Here, we report the successful transmutation of a metallabenzene for pyridine synthesis. This ‘metal-to-nitrogen swapping’ process utilizes readily available ruthenabenzene phosphonium salts and commercially available 2-aminopyridines under mild conditions. The isolation of ruthena-azepines, containing a planar seven-membered aza-metallacycle, along with DFT calculations, supports the nitrogen insertion/metal deletion cascade driven by aromatization. Additionally, we investigate the tunable photophysical properties of the resulting pyridine phosphonium salts.

Full-Link: https://doi.org/10.1038/s41467-025-58855-7