叶龙武

发布日期:2018-04-28     浏览次数:次   

 

教授、博士生导师
电话:0592-2185833
电子邮箱:
longwuye@xmu.edu.cn
课题组网站: https://lwye.xmu.edu.cn/index.htm

个人简历:
博士后 (University of California at Santa Barbara,2009/05-2011/07)
博士后 (The Scripps Research Institute,2008/09-2009/05)
博士 (中科院上海有机所,2003/09-2008/07)
学士 (浙江大学化学系,1999/09-2003/07)

荣誉与获奖:
中科院院长优秀奖 (2008), 中科院优秀毕业生 (2008), 上海市自然科学一等奖 (2011), 福建省杰出青年科学基金 (2015), Thieme Chemistry Journals Award (2016), 国家自然科学基金“优秀青年基金" (2016), 教育部青年长江学者 (2017), 福建省青年拔尖人才 (2017)、厦门大学“田昭武学科交叉奖”一等奖 (2019)等。

研究兴趣:
有机合成方法学:基于炔烃转化的选择性控制与多样性合成; 功能分子合成:生物活性分子、天然产物及药物的合成。

近期主要代表论著:

  1. 1.  B. Zhou, Y.-Q. Zhang, K. Zhang, M.-Y. Yang, Y.-B. Chen, Y. Li, Q. Peng,* S.-F. Zhu,* Q.-L. Zhou, L.-W. Ye,* Stereoselective Synthesis of Medium Lactams Enabled by Metal-Free Hydroalkoxylation/Stereospecific [1,3]-Rearrangement, Nat. Commun. 2019, 10, 3234.

  2. 2. W.-B. Shen, Q. Sun, L. Li, X. Liu, B. Zhou, J.-Z. Yan, X. Lu,* L.-W. Ye,*  Divergent Synthesis of N-Heterocycles via Controllable Cyclization of Azido-Diynes Catalyzed by Copper and Gold, Nat. Commun. 2017, 8, 1748.

  3. 3. Z.-S. Wang, Y.-B. Chen, H.-W. Zhang, Z. Sun, C. Zhu, L.-W. Ye,* Ynamide Smiles Rearrangement Triggered by Visible-Light-Mediated Regioselective Ketyl-Ynamide Coupling: Rapid Access to Functionalized Indoles and Isoquinolines, J. Am. Chem. Soc. 2020, 142, in press.

  4. 4. F.-L. Hong, Z.-S. Wang, D.-D. Wei, T.-Y. Zhai, G.-C. Deng, X. Lu, R.-S. Liu, L.-W. Ye,* Generation of Donor/Donor Copper Carbenes through Copper-Catalyzed Diyne Cyclization: Enantioselective and Divergent Synthesis of Chiral Polycyclic Pyrroles, J. Am. Chem. Soc. 2019, 141, 16961.

  5. 5. C. Shu, Y.-H. Wang, B. Zhou, X.-L. Li, Y.-F. Ping, X. Lu,* L.-W. Ye,* Generation of α-Imino Gold Carbenes through Gold-Catalyzed Intermolecular Reaction of Azides with Ynamides, J. Am. Chem. Soc. 2015, 137, 9567. (Highlighted by JACS Homepage; selected as ESI highly cited papers).

  6. 6. X.-Q. Zhu, Z.-S. Wang, B.-S. Hou, H.-W. Zhang, C. Deng,* L.-W. Ye,* Zinc-Catalyzed Asymmetric Formal [4+3] Annulation of Isoxazoles with Enynol Ethers via 6π Electrocyclization: Stereoselective Access to 2H-Azepines, Angew. Chem. Int. Ed. 2020, 59, 1666.

  7. 7. Y. Xu, Q. Sun, T.-D. Tan, M.-Y. Yang, P. Yuan, S.-Q. Wu, X. Lu,* X. Hong, L.-W. Ye,* Organocatalytic Enantioselective Conia-Ene-Type Carbocyclization of Ynamide-Cyclohexanones: Regiodivergent Synthesis of Morphans and Normorphans, Angew. Chem. Int. Ed. 2019, 58, 16252.

  8. 8. T.-D. Tan, X.-Q. Zhu, H.-Z. Bu, G. Deng, Y.-B. Chen, R.-S. Liu, L.-W. Ye,* Copper-Catalyzed Cascade Cyclization of Indolyl Homopropargyl Amides: Stereospecific Construction of Bridged Aza-[n.2.1] Skeletons, Angew. Chem. Int. Ed. 2019, 58, 9632.

  9. 9. B. Zhou, L. Li, X.-Q. Zhu, J.-Z. Yan, Y.-L. Guo, L.-W. Ye*, Yttrium-Catalyzed Tandem Intramolecular Hydroalkoxylation/Claisen Rearrangement: Efficient Synthesis of Medium-Sized Lactams, Angew. Chem. Int. Ed. 2017, 56, 4015. (selected as ESI highly cited papers).

  10. 10. W.-B. Shen,+ X.-Y. Xiao,+ Q. Sun, B. Zhou, X.-Q. Zhu, J.-Z. Yan, X. Lu,* L.-W. Ye*, Highly Site-Selective Formal [5+2] and [4+2] Annulations of Isoxazoles with Heterosubstituted Alkynes by Platinum Catalysis: Rapid Access to Functionalized 1,3-Oxazepines and 2,5-Dihydropyridines, Angew. Chem. Int. Ed. 2017, 56, 605. (selected as ESI highly cited papers).

  11. 11. L. Li,+ B. Zhou,+ Y.-H. Wang, C. Shu, Y.-F. Pan, X. Lu,* L.-W. Ye,* Zinc-Catalyzed Tandem Alkyne Oxidation/C-H Functionalization: Highly Site-Selective Synthesis of Versatile Isoquinolones and β-Carbolines, Angew. Chem. Int. Ed. 2015, 54, 8245. (Featured in Chin. J. Org. Chem. 2015, 35, 2019 & invited as SYNPACTS article).

  12. 12. L. Li, X.-Q. Zhu, Y.-Q. Zhang, H.-Z. Bu, P. Yuan, J. Chen, J. Su, X. Deng, L.-W. Ye,* Metal-Free Alkene Carbooxygenation Following Tandem Intramolecular Alkoxylation/Claisen Rearrangement: Stereocontrolled Access to Bridged [4.2.1] Lactones, Chem. Sci. 2019, 10, 3123. (selected as the paper of “RSC Editors’ Choice” & ESI highly cited papers).

  13. 13. A.-H. Zhou, Q. He, C. Shu, Y.-F. Yu, S. Liu, T. Zhao, W. Zhang, X. Lu,* L.-W. Ye,* Atom-Economic Generation of Gold Carbenes: Gold-Catalyzed Formal [3+2] Cycloaddition between Ynamides and Isoxazoles, Chem. Sci. 2015, 6, 1265. (selected as the top 1% of highly cited papers of RSC in 2015-2016 & ESI highly cited papers)

  14. 14. L. Li,+ C. Shu,+ B. Zhou, Y.-F. Yu, X.-Y. Xiao, L.-W. Ye,* Generation of Gold Carbenes in Water: Efficient Intermolecular Trapping of the α-Oxo Gold Carbenoids by Indoles and Anilines, Chem. Sci. 2014, 5, 4057.

  15. 15. T.-D. Tan, L.-W. Ye,* Chiral γ-lactam synthesis via asymmetric C-H amidation, Nat. Catal. 2019, 2, 182. (News & Views)

     

     



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