名师讲座
报告题目:Trace metal analysis: the road from speciation to metallomics
报告时间:2025-04-07 10:00
报告人: Prof. Ryszard Lobinski
CNRS, Institute of Analytical and Physical Chemistry for the Environment and Materials (IPREM)
报告地点:卢嘉锡楼202报告厅
转播地点:翔安校区能源材料大楼3号楼会议室5、6,漳州校区生化主楼307教室
报告摘要:
Understanding that the reactivity of trace elements in biology depends on their chemical species has spurred interest in analytical methods targeting specifically the chemical forms of essential and toxic metals and metalloids, leading to the emergence of a field of analytical chemistry known as speciation analysis. Element-specific plasma source detection in chromatography enabled the online detection of sub-picogram quantities of trace elements. Electrospray ionization and advances in high-resolution, high-mass-accuracy (HRAM) mass spectrometry (MS) transformed speciation analysis. Instead of detecting atoms, it became possible to target entire molecules based on accurate mass, focusing on molecular signatures like fine isotopic structure.
The lecture discusses the evolution of speciation analysis leading to the analysis of large populations of chemical species of one or several elements at the same time and their correlation with the biological role (metallomics).
报告人简介:
Ryszard Lobinski graduated as engineer from the Warsaw University of Technology in Poland in 1986, where he obtained his PhD in 1989. He is currently research director at the French National Research Center (CNRS), full professor at the Warsaw University of Technology, and honorary professor at the East China University of Technology. In the years 2015 - 2024, he was the director of the Institute of Analytical and Physical Chemistry for the Environment and Materials (IPREM) in Pau, France. From 2005 to 2009, he served as Vice President and then President of the Analytical Chemistry Division of IUPAC. He was admitted as a Fellow of the RSC (UK) in 2007, and received the CNRS Silver Medal in 2006, the JSPS Award (Japan) in 2011 and the title of doctor honoris causa from the University of Huelva (Spain) in 2024.
In the early 1990s, Ryszard Lobinski was among the pioneers of analytical methods based on coupling separation techniques with plasma-source element-specific detection for speciation analysis. These contributions led to the emergence of metallomics—a field dedicated to comprehensively probing the interactions and functional connections of metal ions and their species with genes, proteins, metabolites, and other biomolecules in biological systems.
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