霍浩华

发布日期:2019-09-10     浏览次数:次   

教授、博导、课题组组长
办公室:卢嘉锡楼607
邮箱:
hhuo@xmu.edu.cn
课题组网站:https://hhuo.xmu.edu.cn/



个人简历:

  • 2019-present  厦门大学化学化工学院,教授、博导

  • 2016-2019   美国加州理工学院(Caltech),博士后 (导师:Gregory.C.Fu 教授)

  • 2012-2016   德国马尔堡大学,博士(导师:Eric Meggers 教授)

  • 2009-2012   厦门大学,硕士,(导师:黄培强、张洪奎 教授)

  • 2005-2009   厦门大学,学士,(导师:黄培强、张洪奎 教授)


个人荣誉:

  • 2022 Thieme Chemistry Journal Award
    2019 国家高层次青年人才
    2017 Resnick 博士后奖学金,Caltech
    2016 德国最高荣誉博士学位论文(summa cum laude)
    2012 优秀硕士毕业生,厦门大学
    2009 优秀本科毕业生,厦门大学
    2009 第五届育苗基金一等奖,厦门大学化学化工学院

研究兴趣:
课题组致力于发展高选择性的催化有机合成技术,解决现代合成化学中反应性和选择性的相关科学瓶颈问题,满足国家现代制药工业的战略技术需求。当前主要研究兴趣包括:不对称廉价过渡金属催化、不对称光催化、药物分子等有机功能分子的不对称合成。

近期主要代表论著:

  1. 1. J. Xu, Z. Li, Y. Xu, X. Shu, H. Huo*, Stereodivergent Synthesis of Both Z- and E-Alkenes by Photoinduced, Ni-Catalyzed Enantioselective C(sp3)–H Alkenylation. ACS Catal. 2021, 11, 13567-13574.

  2. 2. L. Huan, X. Shu, W. Zu, D. Zhong, H. Huo*, “Asymmetric benzylic C(sp3)–H Acylation via dual nickel and photoredox catalysis”, Nat. Commun. 2021, 12, 3536. (featured in Nature Communications Editors’ Highlights, X.S. and L.H. contributed equally.)

  3. 3. X. Shu, L. Huan, Q. Huang, H. Huo*, “Direct Enantioselective C(sp3)–H Acylation for the Synthesis of α-Amino Ketones”, J. Am. Chem. Soc. 2020, 142, 19058-19064. (Highlighted in Synfacts 2021,17, 0040; Organic Chemistry Portal; D. F. Taber, Org. Chem. Highlights 2021, July 12.; X.S. and L.H. contributed equally.)

  4. 4. H. Huo, B. J. Gorsline, G. C. Fu*, “Catalyst-controlled douly enantioconvergent coupling of racemic alkyl nucleophiles and electrophiles”, Science 2020, 367, 559-564. (featured in Science 2020, 367, 509-510highlighted in C&EN as one of sensational syntheses of 2020.)

  5. 5. H. Huo, K. Harms, E. Meggers*, “Catalytic, Enantioselective Addition of Alkyl Radicals to Alkenes via Visible-Light-Activated Photoredox Catalysis with a Chiral Rhodium Complex”, J. Am. Chem. Soc. 2016, 138, 6936-6939.

  6. 6. H. Huo, C. Wang, K. Harms, E. Meggers*, “Enantioselective, Catalytic Trichloromethylation through Visible-Light-Activated Photoredox Catalysis with a Chiral Iridium Complex”, J. Am. Chem. Soc. 2015, 137, 9551-9554.

  7. 7. H. Huo, X. Shen, C. Wang, L. Zhang, P. Röse, L.-A. Chen, K. Harms, M. Marsch, G. Hilt, E. Meggers*, “Asymmetric Photoredox Transition-Metal Catalysis Activated by Visible Light”, Nature 2014, 515, 100-103.

  8. 8. H. Huo, C. Fu, K. Harms, E. Meggers*, “Asymmetric Catalysis with Substitutionally Labile yet Stereochemically Stable Chiral-at-Metal Iridium(III) Complex”, J. Am. Chem. Soc. 2014, 136, 2990-2993.

 

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