【学术报告】生物医用超分子材料

发布日期:2019-08-28     浏览次数:次   

报告人简介:

郭东升博士,南开大学化学学院教授、博导,化学学院副院长。

2001年获南开大学学士学位,2006年获南开大学博士学位,导师刘育教授。2006年留校任教,历任讲师、副教授、教授。2014年成立课题组,主要杯芳烃超分子化学及生物医药应用的研究工作。目前已在Nat. Chem.、Acc. Chem. Res.、Chem. Soc. Rev.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Adv. Mater.、Chem. Sci.等刊物上发表论文100余篇,累计他引3900余次。在国内、外学术交流会议上做学术报告40余次。2013年获国家优秀青年科学基金资助;2014年入选天津市青年拔尖人才支持计划;2018年先后入选天津市、科技部创新人才推进计划中青年科技创新领军人才;2019年入选第四批国家“万人计划”科技创新领军人才。2015年获天津市自然科学一等奖(第二完成人)。目前担任《中国化学快报》青年编委,《Frontiers in Chemistry》编委,全国光功能材料青年学者研讨会学术委员会委员。


报告摘要:生物医用超分子材料

On demand of precision medicine, developing novel biomedical materials is highly appealing. Until now, a lot of nanomaterials, including lipids, polymers, carbon, silica oxides, metal oxides and semiconductor nanocrystals, have been used to formulate nanomedicine that can facilitate better understanding, diagnosis, and treatment of pathological diseases. Supramolecular chemistry has broad potential application for biology and medicine in virtue of molecular recognition and self-assembly. As a result, exploring supramolecular biomedical materials would open an avenue towards precision medicine. Calixarene represents the third generation of supramolecular hosts after crown ether and cyclodextrin. As one family of classical artificial macrocyclic receptors, calixarene shows advantages of facile modification, pre-organized framework and unique binding property. For a few years, we have focused our research interest on biomedical applications by molecular recognition and self-assembly of water-soluble and amphiphilic calixarenes, including biomembrane transport, fluorescent sensing for biomarkers, supramolecular phototheranostics, and inhibiting amyloid fibrillation. In this presentation, I wish to talk about our recent progress on supramolecular biomedical materials based on calixarenes. To be envisaged, calixarene is emerging as one kind of new supramolecular materials for precision medicine with a specialized host-guest recognition site.



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